21 CFR 176.300 - Slimicides.
(a) Slimicides may be safely used in the manufacture of paper and paperboard that contact food, in accordance with the following prescribed conditions:
(1) Slimicides are used as antimicrobial agents to control slime in the manufacture of paper and paperboard.
(2) Subject to any prescribed limitations, slimicides are prepared from one or more of the slime-control substances named in paragraph (c) of this section to which may be added optional adjuvant substances as provided for under paragraph (d) of this section.
(3) Slimicides are added to the process water used in the production of paper or paperboard, and the quantity added shall not exceed the amount necessary to accomplish the intended technical effect.
|List of substances||Limitations|
|Alkenyl (C16-C18) dimethylethyl-ammonium bromide|
|1,2-Benzisothiazolin-3-one||At a level of 0.06 pound per ton of dry weight fiber.|
|1,2-Bis(monobromoacetoxy) ethane [CA Reg. No. 3785-34-0]||At a maximum level of 0.10 pound per ton of dry weight fiber.|
|2-Bromo-2-nitropropane-1,3-diol (CAS Reg. No. 52-51-7)||At a maximum level of 0.6 pound per ton of dry weight fiber.|
|β-Bromo-β-nitrostyrene||At a maximum level of 1 pound per ton of dry weight fiber.|
|5-Chloro-2 - methyl - 4 - isothiazolin-3-one calcium chloride and 2-methyl-4-isothiazolin-3-one calcium chloride mixture at a ratio of 3 parts to 1 part||At a level of 2.5 pounds per ton of dry weight fiber.|
|Chlorinated levulinic acids|
|1,2-Dibromo-2,4-dicyanobutane (CAS Reg. No. 35691-65-7)||At a maximum level of 0.005% of dry weight fiber.|
|2,2-Dibromo-3-nitrilopropionamide||At a maximum level of 0.1 lb/ton of dry weight fiber.|
|4,5-dichloro-1, 2-dithiol-3-one (CAS Reg. No. 1192-52-5)||For use only at levels not to exceed 10 milligrams per kilogram in the pulp slurry.|
|1,3-Dihalo-5,5-dimethylhydantoin (where the dihalo (halogen) may be bromine and/or chlorine) that may contain no more than 20 weight percent 1,3-dihalo-5-ethyl-5-methylhydantoin (where the dihalo (halogen) may be bromine and/or chlorine).||At a maximum level of 1.0 kilogram (kg) per 1,000 kg of dry weight fiber.|
|4-(Diiodomethylsulfonyl) toluene (CAS Reg. No. 20018-09-1).||At a maximum level of 0.2 pound per ton (100 grams/1,000 kilograms) of dry weight fiber.|
|Dipotassium and disodium ethylenebis(dithiocarba-mate)|
||At a maximum level of 0.20 pound per ton of dry weight fiber.|
|Glutaraldehyde (CAS Reg. No. 111-30-8)|
||At a level of 0.02 pound per ton of dry weight fiber.|
|2-Hydroxypropyl methanethiol sulfonate|
|2-Nitrobutyl bromoacetate [CA Reg. No. 32815-96-6]||At a maximum level of 0.15 pound per ton of dry weight fiber.|
|Silver fluoride||Limit of addition to process water not to exceed 0.024 pound, calculated as silver fluoride, per ton of paper produced.|
|Tetrakis(hydroxymethyl)phosphonium sulfate (CAS Reg. No. 55566-30-8)||Maximum use level of 84 mg/kg in the pulp slurry. The additive may also be added to water, which when introduced into the pulp slurry, results in a concentration in the pulp slurry not to exceed 84 mg/kg.|
(d) Adjuvant substances permitted to be used in the preparation of slimicides include substances generally recognized as safe for use in food, substances generally recognized as safe for use in paper and paperboard, substances permitted to be used in paper and paperboard by other regulations in this chapter, and the following:
Title 21 published on 13-Apr-2017 03:05
The following are ALL rules, proposed rules, and notices (chronologically) published in the Federal Register relating to 21 CFR Part 176 after this date.