21 CFR 556.113 - Ceftiofur.

Beta! The text on the eCFR tab represents the unofficial eCFR text at ecfr.gov.
§ 556.113 Ceftiofur.

(a) Acceptable daily intake and acceptable single-dose intake -

(1) Acceptable daily intake (ADI). The ADI for total residues of ceftiofur is 30 micrograms per kilogram of body weight per day.

(2) Acceptable single-dose intake (ASDI). The ASDI total residues of ceftiofur is 0.830 milligrams per kilogram of body weight. The ASDI is the amount of total residues of ceftiofur that may safely be consumed in a single meal. The ASDI is used to derive the tolerance for residues of desfuroylceftiofur at the injection site.

(b) Tolerances -

(1) Poultry, and sheep. A tolerance for residues of ceftiofur in edible tissue is not required.

(2) Swine. The tolerances for desfuroylceftiofur (marker residue) are:

(i) Kidney (target tissue). 0.25 parts per million (ppm).

(ii) Liver. 3 ppm.

(iii) Muscle. 2 ppm.

(3) Cattle. The tolerances for desfuroylceftiofur (marker residue) are:

(i) Kidney (target tissue). 0.4 ppm.

(ii) Liver. 2 ppm.

(iii) Muscle. 1 ppm.

(iv) Milk. 0.1 ppm.

[63 FR 53579, Oct. 6, 1998, as amended at 68 FR 60296, Oct. 22, 2003; 69 FR 43892, July 23, 2004; 71 FR 39546, July 13, 2006]

This is a list of United States Code sections, Statutes at Large, Public Laws, and Presidential Documents, which provide rulemaking authority for this CFR Part.

This list is taken from the Parallel Table of Authorities and Rules provided by GPO [Government Printing Office].

It is not guaranteed to be accurate or up-to-date, though we do refresh the database weekly. More limitations on accuracy are described at the GPO site.

United States Code

Title 21 published on 2015-04-01

The following are ALL rules, proposed rules, and notices (chronologically) published in the Federal Register relating to 21 CFR Part 556 after this date.

  • 2015-10-13; vol. 80 # 197 - Tuesday, October 13, 2015
    1. 80 FR 61293 - New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of a New Animal Drug Application; Change of Sponsor; Change of Sponsor's Address
      GPO FDSys XML | Text
      DEPARTMENT OF HEALTH AND HUMAN SERVICES, Food and Drug Administration
      Final rule; technical amendment.
      This rule is effective October 13, 2015, except for the amendment to 21 CFR 558.460, which is effective October 23, 2015.
      21 CFR Parts 510, 520, 522, 524, 556, and 558