21 CFR 556.113 - Ceftiofur.

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There are 6 Updates appearing in the Federal Register for 21 CFR Part 556. View below or at eCFR (GPOAccess)
§ 556.113 Ceftiofur.

(a)Acceptable daily intake and acceptable single-dose intake -

(1)Acceptable daily intake (ADI). The ADI for total residues of ceftiofur is 30 micrograms per kilogram of body weight per day.

(2)Acceptable single-dose intake (ASDI). The ASDI total residues of ceftiofur is 0.830 milligrams per kilogram of body weight. The ASDI is the amount of total residues of ceftiofur that may safely be consumed in a single meal. The ASDI is used to derive the tolerance for residues of desfuroylceftiofur at the injection site.

(b)Tolerances -

(1)Poultry, and sheep. A tolerance for residues of ceftiofur in edible tissue is not required.

(2)Swine. The tolerances for desfuroylceftiofur (marker residue) are:

(i)Kidney (target tissue). 0.25 parts per million (ppm).

(ii)Liver. 3 ppm.

(iii)Muscle. 2 ppm.

(3)Cattle. The tolerances for desfuroylceftiofur (marker residue) are:

(i)Kidney (target tissue). 0.4 ppm.

(ii)Liver. 2 ppm.

(iii)Muscle. 1 ppm.

(iv)Milk. 0.1 ppm.

[ 63 FR 53579, Oct. 6, 1998, as amended at 68 FR 60296, Oct. 22, 2003; 69 FR 43892, July 23, 2004; 71 FR 39546, July 13, 2006]

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United States Code

Title 21 published on 2015-12-03

The following are ALL rules, proposed rules, and notices (chronologically) published in the Federal Register relating to 21 CFR Part 556 after this date.

  • 2016-12-27; vol. 81 # 248 - Tuesday, December 27, 2016
    1. 81 FR 94991 - New Animal Drugs for Use in Animal Feed; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Applications
      GPO FDSys XML | Text
      DEPARTMENT OF HEALTH AND HUMAN SERVICES, Food and Drug Administration
      Final rule; technical amendment.
      This rule is effective December 30, 2016.
      21 CFR Parts 556 and 558

Title 21 published on 2015-12-03.

The following are only the Rules published in the Federal Register after the published date of Title 21.

For a complete list of all Rules, Proposed Rules, and Notices view the Rulemaking tab.

  • 2016-12-27; vol. 81 # 248 - Tuesday, December 27, 2016
    1. 81 FR 94991 - New Animal Drugs for Use in Animal Feed; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Applications
      GPO FDSys: XML | Text
      DEPARTMENT OF HEALTH AND HUMAN SERVICES, Food and Drug Administration
      Final rule; technical amendment.
      This rule is effective December 30, 2016.
      21 CFR Parts 556 and 558