21 CFR 73.2180 - Guaiazulene.
(1) The color additive, guaiazulene, is principally 1,4-dimethyl-7-isopropyl-azulene.
(2) Color additive mixtures of guaiazulene for cosmetic use may contain the following diluent:
(b)Specifications. Guaiazulene shall conform to the following specifications and shall be free from impurities, other than those named, to the extent that such other impurities may be avoided by good manufacturing practice.
(c)Uses and restrictions. Guaiazulene may be safely used in externally applied cosmetics in amounts consistent with good manufacturing practice.
(e)Exemption from certification. Certification of this color additive for the prescribed use is not necessary for the protection of the public health and therefore batches thereof are exempt from the certification requirements of section 721(c) of the act.