19 CSR 30-1.002 - [Effective until4/10/2022]Schedules of Controlled Substances

Current through Register Vol. 47, No. 7, April 1, 2022

PURPOSE: This emergency amendment updates the Schedules of Controlled Substances to be consistent with 21 CFR Part 1308.

EMERGENCY STATEMENT: The United States Department of Justice Drug Enforcement Administration (DEA) continually evaluates substances to determine their clinical application and potential for abuse. Based on their evaluation, the DEA issues scheduling actions to place substances in the appropriate controlled substance schedules. The majority of these scheduling actions consist of temporarily and permanently scheduling newly-discovered illicit substances in Schedule I. Proper scheduling of these substances allow law enforcement to take action to prevent the further distribution of these substances. Scheduling substances in Schedules II-V allows practitioners to be informed about the potential for addiction/abuse of the substances and prescribe the substances appropriately. Section 195.015, RSMo, charges the department with similarly controlling substances as they are controlled under federal law. Section 195.015.4 requires the Department of Health and Senior Services to submit emergency rules to the Secretary of State within thirty (30) days of a federal scheduling action to allow for similar inclusion, rescheduling, or deletion of controlled substances with this schedule. While this time frame is difficult to achieve given the various approvals and reviews needed prior to the Department scheduling any rule with the Secretary of State, the Department still acts to effectuate these scheduling actions as quickly as possible. This emergency amendment includes all federal scheduling actions since the last amendment of this rule in 2020. This emergency amendment is necessary to protect Missouri's governmental interest in keeping its controlled substances schedules up-to-date as much as practically possible in order to protect its citizens and to aid law enforcement in its prosecution of those who illegally distribute these substances. As a result, the Department of Health and Senior Services finds a compelling governmental interest, which requires this emergency action. A proposed amendment, which covers the same material, is published in this issue of the Missouri Register. The scope of this emergency amendment is limited to the circumstances creating the emergency and complies with the protections extended in the Missouri and United States Constitutions. The Department of Health and Senior Services believes this emergency amendment is fair to all interested persons and parties under the circumstances. Subject to section 536.025, this emergency amendment was filed September 28, 2021, becomes effective October 13, 2021, and expires April 10, 2022.

(1) Schedules of Controlled Substances.
(A) Schedule I shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the Drug Enforcement Administration (DEA) Controlled Substances Code Number set forth opposite it.
1. Opiates. Unless specifically excepted or unless listed in another schedule, any of the following opiates, including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation:

A. Acetyl-alpha-methylfentanyl (N-(1-(1-methyl-2-phenethyl)-4-piperidinyl)-N-phenylacetamide)

9815

B. Acetylmethadol

9601

C. Acetyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide)

9821

D. N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide, its isomers, esters, ethers,salts, and salts of isomers, esters, and ethers (Other names: acryl fentanyl, acryloylfentanyl)

9811

E. AH-7921(3,4-dichloro-N-[(1-dimethylamino) cyclohexylmethyl] benzamide)

9551

F. Allylprodine

9602

G. Alphacetylmethadol (except levoalphacetylmet also known as levo-alpha-acetylmethadol levothadol hadyl acetate or LAAM)

9603

H. Alphameprodine

9604

I. Alphamethadol

9605

J. Alpha-methylfentanyl (N-1-(alphamethyl-beta-phenyl) ethyl-4-piperidyl) propionanilide; 1-(1-methyl-2- phenylethyl)-4 ((N-propanilido) piperidine)

9814

K. Alpha-methylthiofentanyl (N-(1-methyl-2-(2-thienyl) ethyl-4-piperidinyl)-N-phenylpropanamide)

9832

L. Benzethidine

9606

M. Betacetylmethadol

9607

N. Beta-hydroxyfentanyl (N-(1-(2-hydroxy-2-phenethyl)-4-piperidinyl)-N-phenylpropanamide)

9830

O. Beta-hydroxy-3-methylfentanyl (other name: N-(1-(2-hydroxy-2-phenethyl)-3-methyl-4-piperidinyl)-N-phenylpropanamide)

9831

P. N-[1-[2-hydroxy-2-(thiophen- 2-yl) ethyl]piperidin-4-yl]-N-phenylpropionamide (Other names: beta-hydroxythiofentanyl)

9836

Q. Betameprodine

9608

R. Betamethadol

9609

S. beta-Methyl fentanyl (N-phenyl-N-(1-(2-phenylpropyl)piperidin-4-yl) propionamide

(Other name: [BETA]-methyl fentanyl)

9856

T. beta'-Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N,3-diphenylpropanamide (Other names: [BETA]'-phenyl fentanyl; 3-phenylpropanoyl fentanyl)

9842

U. Betaprodine

9611

V. Clonitazene

9612

W. Crotonyl fentanyl ((E)-N-(1-phenethylpiperidin-4-yl)-N-phenylbut-2-enamide)

9844

X. N-(1-phenethylpiperidin-4-yl)-N-Phenylcyclopentanecarboxamide (Other name: cyclopentyl fentanyl)

9847

Y. Cyclopropyl fentanyl (N-(1-phenethylpiperidin-4-yl) -N-phenylcyclopropanecar-boxamide)

9845

Z. Dextromoramide

9613

AA. Diampromide

9615

BB. Diethylthiambutene

9616

CC. Difenoxin

9168

DD. Dimenoxadol

9617

EE. Dimepheptanol

9618

FF. Dimethylthiambutene

9619

GG. Dioxaphetyl butyrate

9621

HH. Dipipanone

9622

II. Ethylmethylthiambutene

9623

JJ. Etonitazene

9624

KK. Etoxeridine

9625

LL. Fentanyl carbamate (ethyl (1-phenethylpiperidin-4-yl)(phenyl)carbamate)

9851

MM. N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide, its isomers, esters, ethrs, ers (Other salts, and salts of isomers, esters, and eth names: 4-fluoroisobutyryl fentanyl, para-fluoroisobutyryl fentanyl)

9824

NN. 2'-Fluoro ortho-fluorofentanyl (N-(1-(2-fluorophenethyl) piperidin-4-yl)-N-(2-fluorophenyl) propionamide (Other names: 2'-fluoro 2-fluorofentanyl)

9855

OO. N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-2-carboxamide (Other names: furanyl fentanyl)

9834

PP. Furethidine

9626

QQ. Hydroxypethidine

9627

RR. N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide (Other name: isobutyryl fentanyl)

9827

SS. Ketobemidone

9628

TT. Levomoramide

9629

UU. Levophenacylmorphan

9631

VV. Methoxyacetyl fentanyl(2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide

9825

WW. 4'-Methyl acetyl fentanyl (N-(1-(4-methylphenethyl) piperidin-4-yl)-N -phenylacetamide)

9819

XX. 3-Methylfentanyl (N-(3-methyl-1-(2-phenylethyl)-4-piperidyl)-N-phenylproanamide), its optical and geometric isomers, salts, and salts of isomers

9813

YY. 3-Methylthiofentanyl (N-(3-methyl-1-(2-thienyl)ethyl-4-piperidinyl)-Nphenylpropanamide)

9833

ZZ. Morpheridine

9632

AAA. MPPP (1-methyl-4-phenyl-4-propionoxypiperidine)

9661

BBB. MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl) piperazine)

(9560)

CCC. Noracymethadol

9633

DDD. Norlevorphanol

9634

EEE. Normethadone

9635

FFF. Norpipanone

9636

GGG. N(2-fluorophenyl)-2-methoxy-N- (1-phenethylpiperidin-4-yl)acetamide, its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers (Other name: ocfentanil)

9838

HHH. ortho-Fluoroacryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4 -yl) acrylamide)

9852

III. ortho-Fluorobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl) butyramide (Other Name: 2-fluorobutyryl fentanyl)

9846

JJJ. ortho-Fluorofentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl) propionamide); other name:2-fluorofentanyl)

9816

KKK. ortho-Fluoroisobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin -4-yl)isobutyramide)

9853

LLL. ortho-Methyl acetylfentanyl (N-(2-methylphenyl)-N-(1-phenethylpiperidin-4-yl) acetamide

(Other name: 2-methyl acetylfentanyl)

9848

MMM. ortho-Methyl methoxyacetyl fentanyl (2-methoxy-N-(2-methylphenyl)-N -(1-phenethylpiperidin-4-yl) acetamide (Other name: 2-methyl methoxyacetyl fentanyl)

9820

NNN. N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide, (Other name: para-chloroisobutyryl fentanyl)

9826

OOO. para-Fluorobutyryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)butyramide)

9823

PPP. Para-fluorofentanyl(N-(4-fluorophenyl)-N- (1-(2-phenethyl)-4-piperidinyl) propanamide

9812

QQQ. para-Fluoro furanyl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)furan-2-carboxamide)

9854

RRR. para-Methoxybutyryl fentanyl (N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl) butyramide)

9837

SSS. para-Methylfentanyl (N-(4-methylphenyl)-N-(1-phenethylpiperidin-4-yl) propionamide (Other Name: 4-methylfentanyl)

9817

TTT. PEPAP (1-(-2-phenethyl)- 4-phenyl-4 acetoxypiperidine)

9663

UUU. Phenadoxone

9637

VVV. Phenampromide

9638

WWW. Phenomorphan

9647

XXX. Phenoperidine

9641

YYY. Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl) -N-phenylbenzamide (Other name: benzoyl fentanyl)

9841

ZZZ. Piritramide

9642

AAAA. Proheptazine

9643

BBBB. Properidine

9644

CCCC. Propiram

9649

DDDD. Racemoramide

9645

EEEE. N-(1-phenethylpiperidin-4-yl)-N-phenyltetrahydrofuran-2-carboxamide, its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers (Other name: tetrahydrofuranyl fentanyl)

9843

FFFF. Thiofentany (N-phenyl-N-(1-(2-thienyl)ethyl-4-piperidinyl)-propanamide

9835

GGGG. Thiofuranyl fentanyl (N-(1-phenethylpiperidin- 4-yl)-N-phenylthiophene-2-carboxamide (Other names: 2-thiofuranyl fentanyl; thiophene fentanyl)

9839

HHHH. Tilidine

9750

IIII. Trimeperidine

9646

2. Opium derivatives. Unless specifically excepted or unless listed in another schedule, any of the following opium derivatives, its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

A. Acetorphine

9319

B. Acetyldihydrocodeine

9051

C. Benzylmorphine

9052

D. Codeine methylbromide

9070

E. Codeine-N-Oxide

9053

F. Cyprenorphine

9054

G. Desomorphine

9055

H. Dihydromorphine

9145

I. Drotebanol

9335

J. Etorphine (except hydrochloride salt)

9056

K. Heroin

9200

L. Hydromorphinol

9301

M. Methyldesorphine

9302

N. Methyldihydromorphine

9304

O. Morphine methylbromide

9305

P. Morphine methylsulfonate

9306

Q. Morphine-N-Oxide

9307

R. Myrophine

9308

S. Nicocodeine

9309

T. Nicomorphine

9312

U. Normorphine

9313

V. Pholcodine

9314

W. Thebacon

9315

3. Opiate Similar Synthetic Substances. Substances scheduled by the United States Drug Enforcement Administration as substances that share a pharmacological profile similar to fentanyl, morphine, and other synthetic opioids, unless specifically excepted or unless listed in another schedule. These substances are-

A. Butyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbutyramide)

9822

B. U-47700 (3,4-Dichloro-N-2-(dimethylamino) cyclohexyl-N-methylbenzamide)

9547

C. N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide (Other name: valeryl fentanyl)

9840

4. Hallucinogenic substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture or preparation, which contains any quantity of the following hallucinogenic substances or which contains any of its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation (For purposes of paragraph (1)(A)4. of this rule only, the term isomer includes the optical, position, and geometric isomers.):

A. Alpha-ethyltryptamine Some trade or other names: etryptamine; Monase; alpha-ethyl-1H-indole-3-ethenamine; 3-(2-aminobutyl)indole; alpha-ET; and AET;

7249

B. 4-bromo-2,5-dimethoxyamphetamine

Some trade or other names: 4-bromo-2, 5- dimethoxy- a-methylphenethylamine; 4-bromo- 2, 5-DMA;

7391

C. 4-bromo-2,5-dimethoxyphenethylamine

7392

D. 2,5-dimethoxyamphetamine

Some trade or other names: 2,5-dimethoxy-amethylphenethylamine; 2,5-DMA;

7396

E. 2,5-dimethoxy-4-ethylamphetamine

Some trade or other names: DOET;

7399

F. 2,5-dimethoxy-4-(n)-propylthiophenethylamine (other name: 2C-T-7)

7348

G. 2-(2,5-Dimethoxy-4-(n)-propylphenyl) ethanamine (2C-P)

7524

H. 2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine (2C-E )

7509

I. 2-(2,5-Dimethoxy-4-methylphenyl) ethanamine (2C-D)

7508

J. 2-(2,5-Dimethoxy-4-nitro-phenyl) ethanamine (2C-N)

7521

K. 2-(2,5-Dimethoxyphenyl) ethanamine (2C-H)

7517

L. 2-(4-Chloro-2,5-dimethoxyphenyl) ethanamine (2C-C)

7519

M. 2-(4-Ethylthio-2,5-dimethoxyphenyl) ethanamine (2C-T-2)

7385

N. 2-(4-Iodo-2,5-dimethoxyphenyl) ethanamine (2C-I)

7518

O. 2-(4-Isopropylthio)-2,5-dimethoxyphenyl) ethanamine (2C-T-4)

7532

P. 4-methoxyamphetamine

Some trade or other names: 4-methoxy-amethylphenethylamine; paramethoxyamphetamine; PMA;

7411

Q. 5-methoxy-3,4-methylenedioxyamphetamine

7401

R. 4-methyl-2,5-dimethoxyamphetamine

Some trade and other names: 4-methyl-2, 5- dimethoxy-a- methylphenethylamine; DOM; and STP;

7395

S. 3,4-methylenedioxyamphetamine

7400

T. 3,4-methylenedioxymetham-phetamine(MDMA)

7405

U. 3,4-methylenedioxy-N-ethylamphetamine (also known as N-ethylalpha-methyl-3,4 (methylenedioxy) phenethylamine, N-ethyl MDA, MDE, and MDEA)

7404

V. N-hydroxy-3,4-methylenedioxyamphetamine (also known as N-hydroxy-alpha-methyl-3,4 (methylenedioxy) phenethylamine and N-hydroxy MDA)

7402

W. 3,4,5-trimethoxyamphetamine

7390

X. 5-MeO-DMT or 5-methoxy-N,N-dimethyltryptamine

7431

Y. Alpha-methyltryptamine

7432

Z. Bufotenine

Some trade and other names: 3-(b-Dimethylaminoethyl)-5-hydrox- yindole; 3-(2-dimethylaminoethyl)-5-indolol; N, N-dimethylsero- tonin; 5-hydroxy-N, N-dimethyltryptamine; mappine;

7433

AA. Diethyltryptamine

Some trade and other names: N, N-Diethyltryptamine; DET;

7434

BB. Dimethyltryptamine

Some trade or other names: DMT;

7435

CC. 5-methoxy-N,N-diisopropyltryptamine (other name: 5-MeODIPT)

7439

DD. Ibogaine

Some trade and other names: 7-Ethyl- 6,6[BETA],7,8,9,10,12,13-octahy- dro-2-methoxy-6, 9-methano-5H-pyrido [1',2':1,2] azepino[5,4-b] indole; Tabernanthe iboga;

7260

EE. Lysergic acid diethylamide

7315

FF. Marihuana

Some trade or other names: marijuana;

7360

GG. Mescaline

7381

HH. Parahexyl

Some trade or other names: 3-Hexyl-1- hydroxy-7,8,9,10-tetrahydro- 6,6,9-trimethyl- 6H-dibenzo[b,d]pyran; Synhexyl;

7374

II. Peyote

Meaning all parts of the plant presently classified botanically as Lophophora williamsii Lemaire, whether growing or not; the seeds thereof; any extract from any part of such plant; and every com- pound, manufacture, salt, derivative, mixture, or preparation of such plant, its seeds, or extracts;

7415

JJ. N-ethyl-3-piperidyl benzilate

7482

KK. N-methyl-3-piperidyl benzilate

7484

LL. Psilocybin

7437

MM. Psilocyn

7438

NN. Tetrahydrocannabinols naturally contained in a plant of the genus Cannabis (cannabis 7370 plant), as well as synthetic equiv- alents of the substances contained in the cannabis plant or in the resinous extractives of such plant, and/or synthetic substances, derivatives, and their isomers, or both, with similar chemical structure and pharmacological activity to those substances contained in the plant, such as the following

(I) 1 cis or trans tetrahydrocannabinol and their optical isomers;

(II) 6 cis or trans tetrahydrocannabinol and their optical isomers;

(III) 3,4 cis or trans tetrahydrocannabinol and its optical isomers; and

(IV) Since nomenclature of these substances is not internationally standardized, compounds of these structures, regardless of numerical designation of atomic positions are covered;

OO. Ethylamine analog of phencyclidine

Some trade or other names: N-ethyl-1- phenylcyclohexylamine, (1- phenylcyclohexyl) ethylamine, N-(1-phenylcyclohexyl)-ethylamine, cyclohexamine, PCE;

7455

PP. Pyrrolidine analog of phencyclidine

Some trade or other names: 1-(1-phenylcyclohexyl)-pyrrolidine PCPy, PHP;

7458

QQ. Thiophene analog of phencyclidine

Some trade or other names: 1-(1-(2-thienyl)- cyclohexyl)-piperidine, 2-thienyl analog of phencyclidine, TPCP, TCP;

7470

RR. 1-(1-(2-thienyl)cyclohexyl) pyrrolidine

Some other names: TCPy;

7473

SS. Salvia divinorum

TT. Salvinorin A

UU. 3-Fluoromethcathinone

1233

VV. 4-Fluoromethcathinone

1238

WW. Mephedrone, or 4-methylmethcathinone

1248

XX. Methylenedioxypyrovalerone, MDPV, or (1-(1,3-Benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1-pentanone

7535

YY. Methylone, or 3,4-Methylenedioxymethcathinone

7540

ZZ. Quinolin-8-yl 1-pentyl-1Hindole-3-carboxylate (PB-22; QUPIC)

7222

AAA. Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (5-fluoro-PB-22; 5F-PB-22)

7225

BBB. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1Hindazole-3-carboxamide (AB-FUBINACA)

7012

CCC. N-(1-amino-3, 3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide(ADB-PINACA)

7035

DDD. (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl) methanone (Other names: UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopro-poyl)indole)

7144

EEE. 1-(5-fluoro-pentyl)-1Hindol-3-yl(2,2,3,3-tetramethylcyclopropyl) methanone (Other names: 5-fluoro-UR-144, 5-F-UR-144, XLR11, 1-(5-fluo-ropentyl)-3-(2,2,3,3-tetramethylcyclopro-poyl)indole)

7011

FFF. N-(1-adamantyl)-1-pentyl-1Hindazole-3-carboxamide (Other names: APINACA, AKB48)

7048

GGG. 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (Other names: 251-NBOMe; 2C-I-NBOMe; 25I; Cimbi-5)

7538

HHH. 2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (Other names: 25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82)

7537

III. 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine (Other names: 25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36)

7536

JJJ. 4-methyl-N-ethylcathinone (Other names: 4-MEC; 2-(ethylamino)-1-(4-methylphenyl)propan-1-one)

1249

KKK. 4-methyl-alphapyrrolid-inopropiophenone, (Other names: 4-MePPP; MePPP; 4-methyl-[ALPHA]-pyrrolidinopropiophenone; 1-(4-methylphenyl)-2-(pyrrolidin-1-yl)-propan-1-one)

7498

LLL. alphapyrrolidinopentio-phenone (Other names: [ALPHA]-PVP; [ALPHA]-pyrrolidinovalerophenone; 1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one)

7545

MMM. Butylone (Other names: bk-MBDB; 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one)

7541

NNN. Pentedrone (Other names: [ALPHA]-methylaminovalerophenone; 2-(methylamino)-1-phenylpentan-1-one)

1246

OOO. Pentylone

(Other names: bk-MBDP; 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one)

7542

PPP. Naphyrone

(Other names: naphthylpyrovalerone; 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one)

1258

QQQ. alpha-pyrrolidinobutio-phenone

(Other names:[ALPHA]-PBP; 1-phenyl-2-(pyrrolidin-1-yl)butan-1-one)

7546

RRR. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (Other names: AB-CHMINACA)

7031

SSS. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1Hindazole-3-carboxamide (Other names: AB-PINACA)

7023

TTT. 1-(5-fluoropentyl)-1H-indazol-3-yl(naphthalen-1-yl)methanone

(Other names: THJ-2201)

7024

UUU. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (Other names: MAB-CHMINACA; ADB-CHMINACA)

7032

VVV. methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (Other names: 5F-ADB; 5F-MDMB- PINACA)

7034

WWW. methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate (Other names: 5F-AMB)

7033

XXX. N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (Other names: 5F- APINACA, 5F-AKB48)

7049

YYY. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (Other names: ADB-FUBINACA)

7010

ZZZ. methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (Other names: MDMB-CHMICA, MMB-CHMINACA)

7042

AAAA. methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate

(Other names: MDMB-FUBINACA)

7020

BBBB. methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate

(Other names: FUB-AMB, MMB-FUBINACA, AMB-FUBINACA)

(7021)

CCCC. 1-(1,3-benzodioxol-5-yl)-2-(ethylamino) propan-1-one (ethylone)

7547

DDDD. Naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (Other names: NM2201; CBL2201)

7221

EEEE. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1 (5-fluoropentyl)-1H-indazole-3-carboxamide

(Other name: 5F-AB-PINACA)

7025

FFFF. 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide (Other names: 4-CN-CUMYLBUTINACA; 4-cyano-CUMYL-BUTINACA; 4-CN-CUMYLBINACA; CUMYL-4CNBINACA; SGT-78)

7089

GGGG. methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-methylbutanoate (Other names: MMB-CHMICA; AMB-CHMICA)

7044

HHHH. 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b] pyridine-3-carboxamide (Other name: 5F-CUMYL-P7AICA)

7085

IIII. N-ethylpentylone (Other names: ephylone, 1-(1,3-benzodioxol-5-yl)-2- (ethylamino)-pentan-1-one)

7543

JJJJ. methyl 2-(1-(4-fluorobutyl) -1H-indazole-3-carboxamido)-3, 3-dimethylbutanoate (4F-MDMB-BINACA, 4F-MDMB-BUTINACA)

7043

KKKK. 1-(4-methoxyphenyl)-N-methylpropan-2-amine

(Other names: para methoxymethamphetamine, PMMA)

1245

LLLL. Synthetic cannabinoids: Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, or which contains their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

(I) Any compound structurally derived from 3-(1-naph-thoyl)indole or 1Hindol- 3-yl-(1-naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2- piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent, whether or not substituted in the naphthyl ring to any extent. Including, but not limited to:

(a) AM2201, or 1-(5-Fluoropentyl)-3-(1-naphthoyl)indole

7201

(b) JWH-007, or 1-pentyl-2-methyl-3-(1-naphthoyl)indole

(c) JWH-015, or 1-propyl-2-methyl-3-(1-naphthoyl)indole

(d) JWH-018, or 1-pentyl-3-(1-naphthoyl)indole

7118

(e) JWH-019, or 1-hexyl-3-(1-naphthoyl)indole

7019

(f) JWH-073, or 1-butyl-3-(1-naphthoyl)indole

7173

(g) JWH-081, or 1-pentyl-3-(4-methoxy-1-naphthoyl)indole

7081

(h) JWH-098, or 1-pentyl-2-methyl-3-(4-methoxy-1-naphthoyl)indole

(i) JWH-122, or 1-pentyl-3-(4-methyl-1-naphthoyl)indole

7122

(j) JWH-164, or 1-pentyl-3-(7-methoxy-1-naphthoyl)indole

(k) JWH-200, or 1-(2-(4-(morpholinyl)ethyl))-3-(1-naphthoyl)indole

7200

(l) JWH-210, or 1-pentyl-3-(4-ethyl-1-naphthoyl)indole

(m) JWH-398, or 1-pentyl-3-(4-chloro-1-naphthoyl)indole

7398

(II) Any compound structurally derived from 3-(1-naph-thoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2- piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the pyrrole ring to any extent, whether or not substituted in the naphthyl ring to any extent;
(III) Any compound structurally derived from 1-(1-naph-thylmethyl)indene by substitution at the 3-position of the indene ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2- piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indene ring to any extent, whether or not substituted in the naphthyl ring to any extent;
(IV) Any compound structurally derived from 3-pheny-lacetylindole by substitution at the nitrogen atom of the indole ring with alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2- piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent, whether or not substituted in the phenyl ring to any extent. Including, but not limited to:

(a) JWH-201, or 1-pentyl-3-(4-methoxyphenylacetyl)indole

(b) JWH-203, or 1-pentyl-3-(2-chloropheny-lacetyl)indole

7203

(c) JWH-250, or 1-pentyl-3-(2-methoxypheny-lacetyl)indole

6250

(d) JWH-251, or 1-pentyl-3-(2-methylphenylacetyl)indole

(e) RCS-8, or 1-(2-cyclohexylethyl)-3-(2-methoxypheny-lacetyl)indole

7008

(V) Any compound structurally derived from 2-(3-hydrox-ycyclohexyl)phenol by substitution at the 5-position of the phenolic ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not substituted in the cyclohexyl ring to any extent. Including, but not limited to:
(a) CP 47,497 & homologues, or 2-[(1R,3S)-3-hydroxy-cyclohexyl]-5-(2-methyloctan-2-yl)phenol), where side chain n=5, and homologues where side chain n-4, 6, or 7 7297, 7298
(VI) Any compound containing a 3- (benzoyl)indole structure with substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to:

(a) AM-694, or 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole

7694

(b) RCS-4, or 1-pentyl-3-(4-methoxybenzoyl)indole (SR-19 and RCS-4)

7104

(VII) CP 50,556-1, or [(6S,6aR,9R,10aR)-9-hydroxy-6-methyl-3-[(2R)-5-phenylpentan-2-yl]oxy-5,6,6a,7,8,9,10,10a-octahydrophenanthridin-1-yl] acetate;
(VIII) HU-210, or (6aR,10aR)-9- (hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7, 10, 10a-tetrahydrobenzochromen-1-ol;
(IX) HU-211, or Dexanabinol,(6aS,10aS)-9-(hydrox-ymethyl)- 6,6-dimethyl-3-(2-methyloctan-2-yl)- 6a,7,10,10a-tetrahy-drobenzochromen-1-ol;
(X) Dimethylheptylpyran, or DMHP.
5. Depressants. Unless specifically excepted or unless listed in another schedule, any material compound, mixture or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

A. Gamma-hydroxybutyric acid and other names GHB; gamma-hydroxybutyrate; 4-hydroxybutyrate; 4-hydroxybutonic acid; sodium oxybate; sodium oxybutryrate

2010

B. Mecloqualone

2572

C. Methaqualone

2565

6. Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers, and salts of isomers:

A. Aminorex

Some trade or other names: aminoxaphen; 2-amino-5-phenyl-2-oxa-zoline; 4,5-dihydro-5-phenyl-2-oxazolamine;

1585

B. N-benzylpiperazine (some other names: BZP, 1-benzylpiperzaine)

7493

C. Cathinone (Some trade or other names: 2-amino-1-phenyl-1-propanone, alphaaminopropiophenone, 2-aminopropiophenone and norephedrone)

1235

D. 4,4'-Dimethylaminorex (4,4'-DMAR; 4,5-dihydro-4-methyl-5-(4-methylphenyl)-2-oxazolamine; 4-methyl-5-(4-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine)

1595

E. Fenethylline

1503

F. Methcathinone

Some trade or other names: 2-(methylamino)- propiophenone; alpha-(methylamino) propiophenone; 2-(methylamino)-1-phenylpropan-1-one; alpha-N-methylaminopropiophenone; monomethylpropion; ephedrone; N-methylcathinone; methylcathinine; AL-464; AL-422; AL-463 and URI 432;

1237

G. 4-methoxymethcathinone

H. cis-4-methylaminorex (cis-4,5-dihydro-4-methyl-5-phenyl-2-oxazolamine)

1590

I. 4-Methyl-alpha-pyrrolidinobutiophenone, or MPBP

J. N-ethylamphetamine

1475

K. N,N-dimethylamphetamine

(some other names: N,N-alpha-trimethylbenzeneethanamine; N,N-alpha-trimethylphenethylamine)

1480

7. A temporary listing of substances subject to emergency scheduling under federal law shall include any material, compound, mixture, or preparation which contains any quantity of the following substances:

A. Fentanyl-related substances, their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers.

9850

(I) Fentanyl-related substance means any substance not otherwise listed under another Administration Controlled Substance Code Number, and for which no exemption or approval is in effect under section 505 of the Federal Food, Drug, and Cosmetic Act 21 U.S.C. 355, that is structurally related to fentanyl by one (1) or more of the following modifications:
(a) Replacement of the phenyl portion of the phenethyl group by any monocycle, whether or not further substituted in or on the monocycle;
(b) Substitution in or on the phenethyl group with alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino, or nitro groups;
(c) Substitution in or on the piperidine ring with alkyl, alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, amino, or nitro groups;
(d) Replacement of the aniline ring with any aromatic monocycle whether or not further substituted in or on the aromatic monocycle; and/or
(e) Replacement of the N-propionyl group by another acyl group.

B. ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate, its optical, positional, and geometric isomers, salts, and salts of isomers (trivial name: 5F-EDMB-PINACA)

7036

C. methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate, its optical, positional, and geometric isomers, salts, and salts of isomers (trivial name: 5F-MDMB-PICA)

7041

D. N-(adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts, and salts of isomers (trivial names: FUB-AKB48; FUB-APINACA; AKB48 N-(4-FLUOROBENZYL))

7047

E. 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts, and salts of isomers (trivial names: 5F-CUMYL-PINACA; SGT-25)

7083

F. (1-(4-fluorobenzyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl) methanone, its optical, positional, and geometric isomers, salts, and salts of isomers (trivial name: FUB-144)

7014

G. N-Ethylhexedrone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other name: 2-(ethylamino)-1-phenylhexan-1-one)

7246

H. alpha-Pyrrolidinohexano-phenone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other names: [ALPHA]-PHP; alpha-pyrrolidinohexiophenone; 1-phenyl-2-(pyrrolidin-1-yl)hexan-1-one)

7544

I. 4-Methyl-alpha-ethylaminopentiophenone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other names: 4-MEAP; 2-(ethylamino)-1-(4-methylphenyl)pentan-1-one)

7245

J. 4'-Methyl-alpha-pyrrolidinohexiophenone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other names: MPHP; 4'-methyl-alpha-pyrrolidinohexano-phenone; 1-(4-methylphenyl)-2-(pyrrolidin-1-yl)hexan-1-one)

7446

K. alpha-Pyrrolidinohepta-phenone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other names: PV8; 1-phenyl-2-(pyrrolidin-1-yl)heptan-1-one)

7548

L. 4'-Chloro-alpha-pyrrolidinovalerophenone, its optical, positional, and geometric isomers, salts, and salts of isomers (Other names: 4-chloro-[ALPHA]-PVP; 4'-chloro-alpha-pyrrolidinopentiophenone; 1-(4-chlorophenyl)-2-(pyrrolidin-1-yl) pentan-1-one)

7443

M. N,N-diethyl-2-(2-(4 isopropoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan-1-amine, its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers (Other names: isotonitazene; N,N-diethyl-2-[[4- (1-methylethoxy)phenyl]methyl]-5-nitro-1H-benzimidazole-1-ethanamine)

9614

N. 1-(1-(1-(4-bromophenyl) ethyl)piperidin-4-yl)-1, 3-dihydro-2H-benzo[d]imidazol-2-one, its isomers, esters, ethers, salts and salts of isomers, esters and ethers (Other names: brorphine; 1-[1-[1-(4-bromophenyl)ethyl]-4-piperidinyl]-1,3-dihydro-2 H-benzimidazol-2-one)

9098

8. Khat, to include all parts of the plant presently classified botanically as catha edulis, whether growing or not; the seeds thereof; any extract from any part of such plant; and every compound, manufacture, salt, derivative, mixture, or preparation of the plant, its seed, or extracts. 7032
(B) Schedule II shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the Controlled Substances Code Number set forth opposite it.
1. Substances, vegetable origin, or chemical synthesis. Unless specifically excepted or unless listed in another schedule, Schedule II shall include any of the following substances whether produced directly or indirectly by extraction from substances of vegetable origin or independently by means of chemical synthesis or by a combination of extraction and chemical synthesis:
A. Opium and opiate; and any salt, compound, derivative, or preparation of opium or opiate, excluding apomorphine, thebainederived butorphanol, dextrorphan, nalbuphine, nalmefene, naloxe-gol, naloxone, and naltrexone and their respective salts, but including the following:

(I) Raw opium

9600

(II) Opium extracts

9610

(III) Opium fluid

9620

(IV) Powdered opium

9639

(V) Granulated opium

9640

(VI) Tincture of opium

9630

(VII) Codeine

9050

(VIII) Dihydroetorphine

9334

(IX) Ethylmorphine

9190

(X) Etorphine hydrochloride

9059

(XI) Hydrocodone

9193

(XII) Hydromorphone

9150

(XIII) Metopon

9260

(XIV) Morphine

9300

(XV) Oripavine

9330

(XVI) Oxycodone

9143

(XVII) Oxymorphone

9652

(XVIII) Thebaine

9333

B. Any salt, compound, derivative, or preparation thereof which is chemically equivalent or identical with any of the substances referred to in subparagraph (1)(B)1.A. of this rule shall be included in Schedule II, except that these substances shall not include the isoquinoline alkaloids of opium;
C. Opium poppy and poppy straw 9650
D. Coca leaves (9040) and any salt, compound, derivative, or preparation of coca leaves (including cocaine (9041) and ecgonine (9180) and their salts, isomers, derivatives, and salts of isomers and derivatives), and any salt, compound, derivative, or preparation thereof which is chemically equivalent or identical with any of these substances, except that the substances shall not include:
(I) Decocainized coca leaves or extraction of coca leaves, which extractions do not contain cocaine or ecgonine; or
(II) Ioflupane;
E. Concentrate of poppy straw (the crude extract of poppy straw in either liquid, solid, or powder form which contains the phenanthrene alkaloids of the opium poppy) 9670
2. Opiates. Unless specifically excepted or unless in another schedule any of the following opiates, including its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation, dextrorphan, and levopropoxyphene excepted:

A. Alfentanil

9737

B. Alphaprodine

9010

C. Anileridine

9020

D. Bezitramide

9800

E. Bulk Dextropropoxyphene (Non-dosage Forms)

9273

F. Carfentanil

9743

G. Dihydrocodeine

9120

H. Diphenoxylate

9170

I. Fentanyl

9801

J. Isomethadone

9226

K. Levo-alphacetylmethadol

Some other names: levo-alphaacetylmethadol, levomethadyl acetate, LAAM

9648

L. Levomethorphan

9210

M. Levorphanol

9220

N. Metazocine

9240

O. Methadone

9250

P. Methadone-Intermediate, 4-cyano-2-dimethylamino-4,4-diphenyl butane

9254

Q. Moramide-Intermediate, 2-methyl-3-morpholino-1, 1-diphenylpropane-carboxylic acid

9802

R. Oliceridine (N-[(3-methoxythiophen-2-yl) methyl] ({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro [4.5]decan-9-yl]ethyl})amine fumarate)

9245

S. Pethidine (Meperidine)

9230

T. Pethidine-Intermediate-A, 4-cyano-1-methyl-4-phenylpiperidine

9232

U. Pethidine-Intermediate-B, ethyl-4-phenylpiperidine-4-carboxylate

9233

V. Pethidine-Intermediate-C, 1-methyl-4-phenylpiperidine-4-carboxylic acid

9234

W. Phenazocine

9715

X. Piminodine

9730

Y. Racemethorphan

9732

Z. Racemorphan

9733

AA. Remifentanil

9739

BB. Sufentanil

9740

CC. Tapentadol

9780

DD. Thiafentanil

9729

3. Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system:

A. Amphetamine, its salts, optical isomers, and salts of its optical isomers

1100

B. Lisdexamfetamine, its salts, isomers, and salts of its isomers

1205

C. Methamphetamine, its salts, isomers, and salts of its isomers

1105

D. Phenmetrazine and its salts

1631

E. Methylphenidate

1724

4. Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

A. Amobarbital

2125

B. Glutethimide

2550

C. Pentobarbital

2270

D. Phencyclidine

7471

E. Secobarbital

2315

5. Hallucinogenic substances:

A. Nabilone

Another name for nabilone: (±)trans-3-(1, 1- dimethylheptyl)-6, 6a,7,8,10,10a-hexahydro- 1-hydroxy-6, 6-dimethyl-9H-dibenzo(b,d) pyran-9-one.

7379

B. Dronabinol [(-)-delta-9-trans tetrahydrocannabinol] in an oral solution in a drug product approved for marketing by the United States Food and Drug Administration.

(7365)

6. Immediate precursors. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances:

A. Immediate precursor to amphetamine and methamphetamine:

(I) Phenylacetone

8501

Some trade or other names: phenyl-2-propanone; P2P; benzyl methyl ketone; methyl benzyl ketone;

B. Immediate precursors to phencyclidine (PCP):

(I) 1-phenylcyclohexylamine

7460

(II) 1-piperidinocyclo-hexanecarbonitrile (PCC)

8603

C. Immediate precursor to fentanyl:

(I) 4-anilino-N-phenethyl-4-piperidine (ANPP)

8333

(II) N-phenyl-N-(piperidin-4-yl)propionamide (norfentanyl)

8366

7. Any material, compound, mixture, or preparation which contains any quantity of the following alkyl nitrites:
A. Amyl nitrite;
B. Butyl nitrite.
(C) Schedule III shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it.
1. Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers (whether optical, position, or geometric), and salts of such isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

A. Those compounds, mixtures, or preparations in dosage unit form containing any stimulant substances listed in Schedule II which compounds, mixtures, or preparations were listed on August 25, 1971, as excepted compounds under 21 CFR 308.32 and any other drug of the quantitive composition shown in that list for those drugs or which is the same except that it contains a lesser quantity of controlled substances

1405

B. Benzphetamine

1228

C. Chlorphentermine

1645

D. Clortermine

1647

E. Phendimetrazine

1615

2. Depressants. Unless specifically excepted or unless listed in another schedule, any material compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system:

A. Any compound, mixture, or preparation containing-

(I) Amobarbital

2126

(II) Secobarbital

2316

(III) Pentobarbital

2271

or any salt thereof and one (1) or more other active medicinal ingredients which are not listed in any schedule;

B. Any suppository dosage form containing-

(I) Amobarbital

2126

(II) Secobarbital

2316

(III) Pentobarbital

or any salt of any of these drugs and approved by the Food and Drug Administration for marketing only as a suppository;

2271

C. Any substance which contains any quantity of a derivative of barbituric acid or any salt thereof

2100

D. Chlorhexadol

2510

E. Embutramide

2020

F. Any drug product containing gamma hydroxybutyric acid, including its salts, isomers, and salts of isomer, for which an appli- cation is approved under section 505 of the Federal Food, Drug, and Cosmetic Act;

2012

G. Ketamine, its salts, isomer, and salts of isomers (some other names for ketamine: (+)-2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone)

7285

H. Lysergic acid

7300

I. Lysergic acid amide

7310

J. Methyprylon

2575

K. Perampanel, and its salts, isomers, and salts of isomers

2261

L. Sulfondiethylmethane

2600

M. Sulfonethylmethane

2605

N. Sulfonmethane

2610

O. Tiletamine and zolazepam or any salt thereof

7295

Some trade or other names for a tiletaminezolazepam combination product: Telazol.

Some trade or other names for tiletamine: 2- (ethylamino)-2-(2-thienyl)-cyclohexanone.

Some trade or other names for zolazepam: 4-(2-fluorophenyl)-6-8-dihydro-1,3,8- trimethylpyrazolo-(3,4-e) (1,4)-diazepin- 7(1H)-one, flupyrazapon.

3. Nalorphine

9400

4. Narcotics drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing limited quantities of any of the following narcotic drugs or any salts thereof:

A. Not more than one and eight tenths grams (1.8gm) of codeine per one hundred milliliters (100 mL) or not more than ninety milligrams (90 mg) per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium

9803

B. Not more than one and eight tenths grams (1.8gm) of codeine per one hundred milliliters (100 mL) or not more than ninety milligrams (90 mg) per dosage unit, with one (1) or more active, nonnarcotic ingredients in recognized therapeutic amounts

9804

C. Not more than one and eight tenths grams (1.8gm) of dihydrocodeine per one hundred milliliters (100 mL) or not more than ninety milligrams (90 mg) per dosage unit, with one (1) or more active, nonnarcotic ingredients in recognized therapeutic amounts

9807

D. Not more than three hundred milligrams (300 mg) of ethylmorphine per one hundred milliliters (100 mL) or not more than fifteen milligrams (15 mg) per dosage unit, with one (1) or more active, nonnarcotic ingredients in recognized therapeutic amounts

9808

E. Not more than five hundred milligrams (500 mg) of opium per one hundred milliliters (100 mL) or per one hundred grams (100 gm) or not more than twenty-five milligrams (25 mg) per dosage unit, with one (1) or more active nonnarcotic ingredients in recognized therapeutic amounts

9809

F. Not more than fifty milligrams (50 mg) of morphine per one hundred milliliters (100 mL) or per one hundred grams (100 gm), with one (1) or more active, nonnarcotic ingredients in recognized therapeutic amounts

9810

5. Any material, compound, mixture, or preparation containing any of the following narcotic drugs or their salts, as set forth below:

A. Buprenorphine

9064

6. Anabolic steroids. Unless specially excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of such salts of isomers is possible within the specific chemical designation. DEA has assigned code 4000 for all anabolic steroids. Anabolic steroids. Any drug or hormonal substance, chemically and pharmacologically related to testosterone (other than estrogens, progestins, corticosteroids, and dehydroepiandrosterone) that promotes muscle growth, except an anabolic steroid which is expressly intended for administration through implants to cattle or other nonhuman species and which has been approved by the Secretary of Health and Human Services for that administration. If any person prescribes, dispenses, or distributes such steroid for human use, such person shall be considered to have prescribed, dispensed, or distributed an anabolic steroid within the meaning of this paragraph. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any quantity of the following substances, including its salts, esters, and ethers:
A. 3[BETA],17[BETA]-dihydroxy-5[ALPHA]-androstane
B. 3[ALPHA],17[BETA]-dihydroxy-5[ALPHA]-androstane
C. 5[ALPHA]-androstan-3,17-dione
D. 1-androstenediol (3[BETA],17[BETA]-dihydroxy-5[ALPHA]-androst-1-ene)
E. 1-androstenediol (3[ALPHA],17[BETA]-dihydroxy-5[ALPHA]-androst-1-ene)
F. 4-androstenediol (3[BETA],17[BETA]-dihydroxy-androst-4-ene)
G. 5-androstenediol (3[BETA],17[BETA]-dihydroxy-androst-5-ene)
H. 1-androstenedione ([5[ALPHA]]-androst-1-en-3,17-dione)
I. 4-androstenedione (androst-4-en-3,17-dione)
J. 5-androstenedione (androst-5-en-3,17-dione)
K. Bolasterone (7[ALPHA],17[ALPHA]-dimethyl-17[BETA]-hydroxyandrost-4-en-3- one)
L. Boldenone (17[BETA]-hydroxyandrost-1, 4-diene-3-one)
M. Boldione (androstra-1,4-diene-3,17-dione)
N. Calusterone (7[BETA],17[ALPHA]-dimethyl-17[BETA]-hydroxyandrost-4-en-3-one)
O. Clostebol (4-chloro-17[BETA]-hydroxyandrost-4-en-3-one)
P. Dehydrochloromethyltestosterone (4-chloro-17[BETA]-hydroxy-17[ALPHA]-methyl-androst-1, 4-dien-3-one)
Q. Desoxymethyltestosterone (17[ALPHA]-methyl-5[ALPHA]-androst-2-en-17[BETA]-ol) (a.k.a. madol)
R. [DELTA]1-dihydrotestosterone (a.k.a.'1-testosterone')(17[BETA]-hydroxy-5[ALPHA]-androst-1-en-3-one)
S. 4-dihydrotestosterone (17[BETA]-hydroxy-androstan-3-one)
T. Drostanolone (17[BETA]-hydroxy-2[ALPHA]-methyl-5[ALPHA]-androstan-3-one)
U. Ethylestrenol (17[ALPHA]-ethyl-17[BETA]-hydroxyestr-4-ene)
V. Fluoxymesterone (9-fluoro-17[ALPHA]-methyl-11[BETA],17[BETA]-dihydrox-yandrost-4-en-3-one)
W. Formebulone (Formebolone) (2-formyl-17[ALPHA]-methyl-11[ALPHA],17[BETA]-dihydroxyandrost-1,4-dien-3-one)
X. Furazabol (17[ALPHA]-methyl-17[BETA]-hydroxyandrostano[2,3-c]-furazan)
Y. 13[BETA]-ethyl-17[BETA]-hydroxygon-4-en-3-one
Z. 4-hydroxytestosterone (4,17[BETA]-dihydroxy-androst-4-en-3-one)
AA. 4-hydroxy-19-nortestosterone (4,17[BETA]-dihydroxy-estr-4-en-3-one)
BB. Mestanolone (17[ALPHA]-methyl-17[BETA]-hydroxy-5[ALPHA]-androstan-3-one)
CC. Mesterolone (1[ALPHA]-methyl-17[BETA]-hydroxy-[5[ALPHA]]-androstan-3-one)
DD. Methandienone (17[ALPHA]-methyl-17[BETA]-hydroxyandrost-1,4-dien-3-one)
EE. Methandriol (17[ALPHA]-methyl-3[BETA],17[BETA]-dihydroxyandrost-5-ene)
FF. Methasterone (2[ALPHA],17[ALPHA]-dimethyl-5[ALPHA]-androstan-17[BETA]-ol-3-one)
GG. Methenolone (1-methyl-17[BETA]-hydroxy-5[ALPHA]-androst-1-en-3-one)
HH. 17[ALPHA]-methyl-3[BETA],17[BETA]-dihydroxy-5[ALPHA]-androstane
II. 17[ALPHA]-methyl-3[ALPHA],17[BETA]-dihydroxy-5[ALPHA]-androstane
JJ. 17[ALPHA]-methyl-3[BETA],17[BETA]-dihydroxyandrost-4-ene
KK. 17[ALPHA]-methyl-4-hydroxynandrolone(17[ALPHA]-methyl-4-hydroxy-17[BETA]-hydroxyestr-4- en-3-one)
LL. Methyldienolone (17[ALPHA]-methyl-17[BETA]-hydroxyestra-4,9(10)-dien-3-one)
MM. Methyltrienolone (17[ALPHA]-methyl-17[BETA]-hydroxyestra-4,9,11-trien-3-one)
NN. Methyltestosterone (17[ALPHA]-methyl-17-hydroxyandrost-4-en-3-one)
OO. Mibolerone (7[ALPHA],17[ALPHA]-dimethyl-17[BETA]-hydroxyestr-4-en-3-one)
PP. 17[ALPHA]-methyl-â 1-dihydrotestosterone (17[BETA]-hydroxy-17[ALPHA]-methyl-5[ALPHA]-androst-1-en-3-one) (a.k.a. 17-[ALPHA]-methyl-1-testosterone)
QQ. Nandrolone (17[BETA]-hydroxyestr-4-ene-3-one)
RR. 19-nor-4-androstenediol (3[BETA],17[BETA]-dihydroxyestr-4-ene)
SS. 19-nor-4-andro stenediol (3[ALPHA],17[BETA]-dihydroxyestr-4-ene)
TT. 19-nor-4,9(10)-androstadienedione (estra-4,9(10)-diene-3,17-dione)
UU. 19-nor-5-androstenediol (3[BETA],17[BETA]-dihydroxyestr-5-ene)
VV. 19-nor-5-androstenediol (3[ALPHA],17[BETA]-dihydroxyestr-5-ene)
WW. 19-nor-4-androstenedione (estr-4-en-3,17-dione)
XX. 19-nor-5-androstenedione (estr-5-en-3,17-dione)
YY. Norbolethone (13[BETA],17[ALPHA]-diethyl-17[BETA]-hydroxygon-4-en-3-one)
ZZ. Norclostebol (4-chloro-17[BETA]-hydroxyestr-4-en-3-one)
AAA. Norethandrolone (17[ALPHA]-ethyl-17[BETA]-hydroxyestr-4-en-3-one)
BBB. Normethandrolone (17[ALPHA]-methyl-17[BETA]-hydroxyestr-4-en-3-one)
CCC. Oxandrolone (17[ALPHA]-methyl-17[BETA]-hydroxy-2-oxa-[5[ALPHA]]-androstan-3-one)
DDD. Oxymesterone (17[ALPHA]-methyl-4,17[BETA]-dihydroxyandrost-4-en-3-one)
EEE. Oxymetholone (17[ALPHA]-methyl-2-hydroxymethylene-17[BETA]-hydroxy-[5[ALPHA]]-androstan-3-one)
FFF. Prostanozol (17[BETA]-hydroxy-5[ALPHA]-androstano3,2-cpyra-zole)
GGG. Stanolone ([DELTA]1-dihydrotestosterone (a.k.a. 1-testos-terone)(17[BETA]-hydroxy-5[ALPHA]-androst-1-en-3-one))
HHH. Stanozolol (17[ALPHA]-methyl-17[BETA]-hydroxy-[5[ALPHA]]-androst-2-eno[3,2-c]-pyrazole)
III. Stenbolone (17[BETA]-hydroxy-2-methyl-[5[ALPHA]]-androst-1-en-3-one)
JJJ. Testolactone(13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid lactone)
KKK. Testosterone(17[BETA]-hydroxyandrost-4-en-3-one);
LLL. Tetrahydrogestrinone (13[BETA],17[ALPHA]-diethyl-17[BETA]-hydroxy-gon-4,9, 11-trien-3-one)
MMM. Trenbolone (17[BETA]-hydroxyestr-4,9,11-trien-3-one)
NNN. Any salt, ester, or isomer of a drug or substance described or listed in this subparagraph, if that salt, ester, or isomer promotes muscle growth except an anabolic steroid which is expressly intended for administration through implants to cattle or other nonhuman species and which has been approved by the secretary of Health and Human Services for that administration.

7. Dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in a United States Food and Drug Administration approved drug product

(Some other names for dronabinol: (6aRtrans)- 6a,7,8,10a-tetrahy-dro-6.6.9-trimethyl-3-pentyl-6H-dibenzo (b,d) pyran-1-ol, or (-) -delta-9-(trans)-tetrahydrocannabinol.)

7369

(D) Schedule IV shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it.
1. Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing limited quantities of any of the following narcotic drugs or any salts thereof:

A. Not more than one milligram (1 mg) of difenoxin (DEA Drug Code No. 9168) and not less than twenty-five micrograms (25 mcg) of atropine sulfate per dosage unit

9167

B. Dextropropoxyphene (alpha-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane)

9278

C. 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclo-hexanol, its salts, optical and geometric isomers, and salts of these isomers (including tramadol)

9752

D. Narcotic drugs containing nonnarcotic active medicinal ingredients. Any compound, mixture, or preparation containing any of the following limited quantities of narcotic drugs or salts thereof, which shall include one (1) or more nonnarcotic active medicinal ingredients in sufficient proportion to confer upon the compound, mixture, or preparation valuable medicinal qualities other than those possessed by the narcotic drug alone:

(I) Not more than two hundred milligrams (200 mg) of codeine per one hundred milliliters (100 mL) or per one hundred grams (100 gm);

(II) Not more than one hundred milligrams (100 mg) of dihydrocodeine per one hundred milliliters (100 mL) or per one hundred grams (100 gm); or

(III) Not more than one hundred milligrams (100 mg) of ethylmorphine per one hundred milliliters (100 mL) or per one hundred grams (100 gm).

2. Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

A. Alfaxalone

2731

B. Alprazolam

2882

C. Barbital

2145

D. Brexanolone

2400

E. Bromazepam

2748

F. Camazepam

2749

G. Carisoprodol

8192

H. Chloral betaine

2460

I. Chloral hydrate

2465

J. Chlordiazepoxide

2744

K. Clobazam

2751

L. Clonazepam

2737

M. Clorazepate

2768

N. Clotiazepam

2752

O. Cloxazolam

2753

P. Delorazepam

2754

Q. Diazepam

2765

R. Dichloralphenazone

2467

S. Estazolam

2756

T. Ethchlorvynol

2540

U. Ethinamate

2545

V. Ethyl loflazepate

2758

W. Fludiazepam

2759

X. Flunitrazepam

2763

Y. Flurazepam

2767

Z. Fospropofol

2138

AA. Halazepam

2762

BB. Haloxazolam

2771

CC. Ketazolam

2772

DD. Lemborexant

2245

EE. Loprazolam

2773

FF. Lorazepam

2885

GG. Lormetazepam

2774

HH. Mebutamate

2800

II. Medazepam

2836

JJ. Meprobamate

2820

KK. Methohexital

2264

LL. Methylphenobarbital (Mephobarbital)

2250

MM. Midazolam

2884

NN. Nimetazepam

2837

OO. Nitrazepam

2834

PP. Nordiazepam

2838

QQ. Oxazepam

2835

RR. Oxazolam

2839

SS. Paraldehyde

2585

TT. Petrichloral

2591

UU. Phenobarbital

2285

VV. Pinazepam

2883

WW. Prazepam

2764

XX. Quazepam

2881

YY. Remimazolam

2846

ZZ. Suvorexant

2223

AAA. Temazepam

2925

BBB. Tetrazepam

2886

CCC. Triazolam

2887

DDD. Zaleplon

2781

EEE. Zolpidem

2783

FFF. Zopiclone

2784

3. Fenfluramine. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers (whether optical, position, or geometric), and salts of such isomers, whenever the existence of such salts, isomers, and salts of isomers is possible:

A. Fenfluramine

1670

4. Lorcaserin. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers, whenever the existence of such salts, isomers, and salts of isomers is possible:

A. Lorcaserin

1625

5. Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers, and salts of isomers:

A. Cathine ((+)-norpseudoephedrine)

1230

B. Diethylpropion

1610

C. Fencamfamin

1760

D. Fenproporex

1575

E. Mazindol

1605

F. Mefenorex

1580

G. Modafinil

1680

H. Pemoline (including organometallic complexes and chelates thereof)

1530

I. Phentermine

1640

J. Pipradrol

1750

K. Serdexmethylphenidate

1729

L. Sibutramine

1675

M. Solriamfetol (2-amino-3-phenylpropyl carbamate; benzenepropanol, betaamino-, carbamate (ester))

1650

N. SPA (-)-1-dimethylamino-1,2-diphenylethane

1635

6. Other substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts:

A. Pentazocine

9709

B. Butorphanol (including its optical isomers)

9720

C. Eluxadoline (5-[[[(2S)-2- amino-3-[4-aminocarbonyl)- 2,6-dimethylphenyl]-1- oxopropyl] [(1S)-1-(4-phenyl- 1 H-imidazol-2- yl)ethyl]amino]methyl]-2- methoxybenzoic acid) (including its optical isomers) and its salts, isomers, and salts of isomers

9725

7. Ephedrine. Any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system including their salts, isomers, and salts of isomers:
A. Ephedrine or its salts, optical isomers, or salts of optical isomers as the only active medicinal ingredient or contains ephedrine or its salts, optical isomers, or salts of optical isomers and therapeutically insignificant quantities of another active medicinal ingredient.
(E) Schedule V shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this subsection.
1. Narcotic drugs containing nonnarcotic active medicinal ingredients. Any compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as follows, which shall include one (1) or more nonnarcotic active medicinal ingredients in sufficient proportion to confer upon the compound, mixture, or preparation valuable medicinal qualities other than those possessed by the narcotic drug alone:
A. Not more than two hundred milligrams (200 mg) of codeine per one hundred milliliters (100 mL) or per one hundred grams (100 gm);
B. Not more than one hundred milligrams (100 mg) of dihydrocodeine per one hundred milliliters (100 mL) or per one hundred grams (100 gm);
C. Not more than one hundred milligrams (100 mg) of ethylmorphine per one hundred milliliters (100 mL) or per one hundred grams (100 gm);
D. Not more than two and five-tenths milligrams (2.5 mg) of diphenoxylate and not less than twenty-five micrograms (25 mcg) of atropine sulfate per dosage unit;
E. Not more than one hundred milligrams (100 mg) of opium per one hundred milliliters (100 mL) or per one hundred grams (100 gm); and
F. Not more than five-tenths milligram (0.5 mg) of difenoxin (DEA Drug Code No. 9168) and not less than twenty-five micrograms (25 mcg) of atropine sulfate per dosage unit.
2. Stimulants. Unless specifically exempted or excluded or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system including its salts, isomers, and salts of isomers:

A. Pyrovalerone

1485

3. Any compound, mixture, or preparation containing any detectable quantity of pseudoephedrine or its salts or optical i somers, or salts of optical isomers or any compound, mixture, or preparation containing any detectable quantity of ephedrine or its salts or optical isomers, or salts of optical isomers if the drug preparations are starch-based solid dose forms, if such preparations are sold over the counter without a prescription. The following drug preparations containing ephedrine and pseudoephedrine are not scheduled controlled substances:
A. Drug preparations in liquid form;
B. Drug preparations that require a prescription in order to be dispensed.
4. Unless specifically exempted or excluded or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts:

A. Ezogabine [N-[2-amino-4(4- fluorobenzylamino)-phenyl]- carbamic acid ethyl ester]

2779

B. Lacosamide [(R)-2- acetoamido-N-benzyl- 3-methoxy-propionamide]

2746

C. Pregabalin [(S)-3- (aminomethyl)-5- methylhexanoic acid]

2782

D. Brivaracetam ((25)-2-[(4R)- 2-oxo-4-propylpyrrolidin-1- yl]butanamide) (also referred to as BRV; UCB-34714; Briviact)

2710

E. Lasmiditan [2,4,6- trifluoro-N-(6-(1- methylpiperidine-4-carbonyl) pyridine-2- yl-benzamide]

2790

F. Cenobamate ([(1R)-1-(2- chlorophenyl)-2-(tetrazol- 2-yl)ethyl] carbamate; 2H- tetrazole-2-ethanol, alpha-(2- chlorophenyl)-, carbamate (ester), (alphaR)-; carbamic acid (R)-(+)-1-(2- chlorophenyl)-2-(2H-tetrazol- 2-yl)ethyl ester)

2720

(2) Excluded Nonnarcotic Substances. The following nonnarcotic substances which, under the Federal Food, Drug, and Cosmetic Act ( 21 U.S.C. 301 ) and section 201(g)(1) of the federal Controlled Substances Act ( 21 U.S.C. 811(g)(1) ), may be lawfully sold over the counter without a prescription, are excluded from all schedules pursuant to section 195.015(5), RSMo.

Excluded Nonnarcotic Products

Company

Trade Name

NDC Code

Form

Controlled Substance

mg or mg/mL

Bioline Laboratories

Theophed

00719-1945

TB

Phenobarbital

8.00

Aphena Pharma Solutions-New York, LLC

Nasal decongestant/ inhaler/vapor

Levometamfetamine (l-desoxyephedrine)

50.00

Goldline Laboratories

Guiaphed Elixir

00182-1377

EL

Phenobarbital

4.00

Goldline Laboratories

Tedrigen Tablets

00182-0134

TB

Phenobarbital

8.00

Hawthorne Products, Inc.

Choate's Leg Freeze

LQ

Chloral hydrate

246.67

Parke-Davis & Co.

Tedral

00071-0230

TB

Phenobarbital

8.00

Parke-Davis & Co.

Tedral Elixir

00071-0242

EX

Phenobarbital

40.00

Parke-Davis & Co.

Tedral S.A.

00071-0231

TB

Phenobarbital

8.00

Parke-Davis & Co.

Tedral Suspension

00071-0237

SU

Phenobarbital

80.00

Parmed Pharmacy

Asma-Ese

00349-2018

TB

Phenobarbital

8.10

Rondex Labs

Azma-Aids

00367-3153

TB

Phenobarbital

8.00

Smith Kline Consumer

Benzedrex

49692-0928

IN

Propylhexedrine

250.00

Sterling Drug, Inc.

Bronkolixir

00057-1004

EL

Phenobarbital

0.80

Sterling Drug, Inc.

Bronkotabs

00057-1005

TB

Phenobarbital

8.00

Vicks Chemical Co.

Vicks Inhaler

23900-0010

IN

I-Desoxyephedrine

113.00

White Hall Labs

Primatene (P-tablets)

00573-2940

TB

Phenobarbital

8.00

Notes

19 CSR 30-1.002
Amended by Missouri Register November 1, 2021/Volume 46, Number 21, effective 10/13/2021

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