N.J. Admin. Code 26D app 11

Current through Register Vol. 54, No. 7, April 4, 2022

TOXICITY FACTORS USED IN THE DEVELOPMENT OF THE REMEDIATION STANDARDS

Table 1-Soil Ingestion-Dermal Toxicity Factors

Contaminant CAS No. Soil Ingestion-dermal Recommendation Soil Ingestion-dermal Toxicity Factor(s)
Acenaphthene 83-32-9 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1994) 0.06 mg/kg-day ABS 0.13
Acetone 67-64-1 IRIS RfD IRIS RfD (2003) 0.9 mg/kg-day
Acetophenone 98-86-2 IRIS RfD IRIS RfD (1989) 0.1 mg/kg-day
Aldrin 309-00-2 IRIS Slope Factor (SF) RfD IRIS SF (1993) 17 (mg/kg-day)-1 IRIS RfD (1988) 0.00003 mg/kg-day
Aluminum 7429-90-5 PPRTV RfD PPRTV RfD (2006) 1.0 mg/kg-day
Anthracene 120-12-7 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1993) 0.3 mg/kg-day ABS 0.13
Antimony 7440-36-0 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (1991) 0.0004 mg/kg-day GIABS 0.15
Arsenic 7440-38-2 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS SF (1998) 1.5 (mg/kg-day)-1 IRIS RfD (1993) 0.0003 mg/kg-day ABS 0.03
Atrazine 1912-24-9 IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor IRIS RfD (1993) 0.035 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Barium 7440-39-3 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (2005) 0.2 mg/kg-day GIABS 0.07
Benzaldehyde 100-52-7 PPRTV Slope Factor (SF) IRIS RfD PPRTV SF (2015) 4E-03 (mg/kg-day)-1 IRIS RfD (1988) 0.1 mg/kg-day
Benzene 71-43-2 NJDWQI Slope Factor (SF) IRIS RfD1 NJDWQI SF (1994) 0.23 (mg/kg-day)-1 IRIS RfD (2003) 0.004 mg/kg-day
Benzo(a)anthracene 56-55-3 IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(a) pyrene) with a dermal absorption fraction (ABS) IRIS SF (2017) 1.0E-01(mg/kg-day)-1 (adjusted for benzo (a)anthracene) ABS 0.13
Benzo(a)pyrene 50-32-8 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (2017) 1.0E +00 (mg/kg-day)-1
IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (2017) 3.0E-04 mg/kg-day ABS 0.13
IRIS Slope Factor (SF) (benzo(a)pyrene - IRIS SF (2017) 1.0E-01 (mg/kg-
Benzo(b)fluoranthene 205-99-2 adjusted for benzo(b) fluoranthene) with a dermal absorption fraction (ABS) day)-1 (adjusted for benzo (b)fluoranthene) ABS 0.13
Benzo(k)fluoranthene 207-08-9 IRIS Slope Factor (SF) (benzo(a)pyrene -adjusted for benzo(k) fluoranthene) with a dermal absorption fraction (ABS) IRIS SF (2017) 1.0E-02(mg/kg-day)-1 (adjusted for benzo(k) fluoranthene) ABS 0.13
Beryllium 7440-41-7 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (1998) 0.002 mg/kg-day GIABS 0.007 IRIS SF (2013)
1,1'-Biphenyl 92-52-4 IRIS Slope Factor (SF) IRIS RfD 0.008 (mg/kg-day)- 1 IRIS RfD (2013) 0.5 mg/kg-day
Bis(2-chloroethoxy) methane 111-91-1 PPRTV RfD with a dermal absorption fraction (ABS) PPRTV RfD (2006) 0.003 mg/kg-day ABS 0.1
Bis(2-chloroethyl) ether 111-44-4 IRIS Slope Factor (SF) IRIS SF (1994) 1.1 (mg/kg-day)-1
Bis(2-ethylhexyl) phthalate 117-81-7 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS SF (1993) 0.014 (mg/kg-day)-1 IRIS RfD (2013) 0.02 mg/kg-day ABS 0.1
Bromodichloromethane 75-27-4 IRIS Slope Factor (SF) IRIS RfD IRIS SF (1993) 0.062 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day IRIS SF (1991)
Bromoform 75-25-2 IRIS Slope Factor (SF) IRIS RfD 0.0079 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day
Bromomethane 74-83-9 IRIS RfD IRIS RfD (1991) 0.0014 mg/kg-day
2-Butanone 78-93-3 IRIS RfD2 IRIS RfD (2003) 0.6 mg/kg-day
Butylbenzylphthalate 85-68-7 PPRTV Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor PPRTV SF (2002) 0.0019 (mg/kg-day)-1 IRIS RfD (2013) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Cadmium 7440-43-9 IRIS RfD with a dermal absorption fraction (ABS) and gastrointestinal absorption fraction (GIABS) IRIS RfD (1994) 0.001 mg/kg-day ABS 0.001 GIABS 0.025
Caprolactam 105-60-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1988) 0.5 mg/kg-day ABS 0.1
Carbon disulfide 75-15-0 No ingestion-based toxicity factors are available None
Carbon tetrachloride 56-23-5 NJDWQI Slope Factor (SF) IRIS RfD NJDWQI SF (1994) 0.091 (mg/kg-day)-1 IRIS RfD (2011) 0.004 mg/kg-day
Chlordane (alpha plus gamma mix ture) 57-74-9 NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) PPRTV Slope Factor (SF) with a dermal absorption NJDWQI SF (2001) 2.3 (mg/kg-day)-1 IRIS RfD (1998) 0.0005 mg/kg-day ABS 0.04 PPRTV SF (2008) 0.2 (mg/kg-day)-1
4-Chloroaniline 106-47-8 fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1995) 0.004 mg/kg-day ABS 0.1
Chlorobenzene 108-90-7 NJDWQI RfD NJDWQI RfD (1994) 0.0065 mg/kg-day
Chloroethane 75-00-3 No ingestion-based toxicity factors are available None
Chloroform 67-66-3 IRIS RfD3 IRIS RfD (2001) 0.01 mg/kg-day
Chloromethane 74-87-3 No ingestion-based toxicity factors are available None
2-Chloronaphthalene 91-58-7 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1990) 0.08 mg/kg-day ABS 0.13
2-Chlorophenol 95-57-8 IRIS RfD IRIS RfD (1993) 0.005 mg/kg-day
Chrysene 218-01-9 IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for chrysene) with a dermal absorption fraction (ABS) IRIS SF (2017) 1.0E-03 (mg/kg-day)-1 (adjusted for chrysene) ABS 0.13
Cobalt 7440-48-4 PPRTV RfD PPRTV RfD (2008) 0.0003 mg/kg-day
Copper 7440-50-8 HEAST RfD HEAST RfD (1997) 0.04 mg/kg-day
Cyanide 57-12-5 IRIS RfD IRIS RfD (2010) 0.0006 mg/kg-day
Cyclohexane 110-82-7 No ingestion-based toxicity factors are available None
4,4'-DDD 72-54-8 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1988) 0.24 (mg/kg-day)-1 ABS 0.1
4,4'-DDE 72-55-9 IRIS SF
4,4'-DDT 50-29-3 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS SF (1991) 0.34 (mg/kg-day)-1 IRIS RfD (1996) 0.0005 mg/kg-day ABS 0.03
Dibenz(a,h)anthracene 53-70-3 IRIS Slope Factor (SF) (benzo(a)pyrene-adjusted for dibenz(a,h) anthracene) with a dermal absorption fraction (ABS) IRIS SF (2017) 1.0E+00 (mg/kg-day)-1 (adjusted for dibenz(a,h) anthracene) ABS 0.13
Dibromochloromethane 124-48-1 IRIS Slope Factor (SF) IRIS RfD and a Group C carcinogen factor IRIS SF (1992) 0.084 (mg/kg-day)-1 IRIS RfD (1991) 0.02 mg/kg-day Group C carcinogen factor 10 PPRTV SF (2006)
1,2-Dibromo-3-chloropropane 96-12-8 PPRTV Slope Factor (SF) PPRTV RfD 0.8 (mg/kg-day)-1 PPRTV RfD (2006) 0.0002 mg/kg-day IRIS SF (2004)
1,2-Dibromoethane 106-93-4 IRIS Slope Factor (SF) IRIS RfD 2.0 (mg/kg-day)-1 IRIS RfD (2004) 0.009 mg/kg-day NJDWQI RfD
1,2-Dichlorobenzene 95-50-1 NJDWQI RfD (1994) 0.086 mg/kg-day NJDWQI RfD
1,3-Dichlorobenzene 541-73-1 NJDWQI RfD (1994) 0.086 mg/kg-day NJDWQI RfD (1994)
NJDWQI RfD with a 0.01 mg/kg-day
1,4-Dichlorobenzene 106-46-7 Group C carcinogen (RfD includes
factor4 Group C Carcinogen factor adjustment of 10)
3,3'-Dichlorobenzidine 91-94-1 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1993) 0.45 (mg/kg-day)-1 ABS 0.1
Dichlorodifluoromethane 75-71-8 IRIS RfD IRIS RfD (1995) 0.2 mg/kg-day
CalEPA SF (1992)
1,1-Dichloroethane 75-34-3 CalEPA Slope Factor (SF) PPRTV RfD5 0.0057 (mg/kg- day)-1 PPRTV RfD (2006) 0.2 mg/kg-day
1,2-Dichloroethane 107-06-2 NJDWQI Slope Factor (SF)6 NJDWQI SF (1994) 0.12 (mg/kg-day)-1
NJDWQI RfD (1994)
NJDWQI RfD with a 0.00014 mg/kg-day
1,1-Dichloroethene 75-35-4 Group C carcinogen (RfD includes
factor Group C Carcinogen factor adjustment of 10)
NJDWQI RfD
cis-1,2-Dichloroethene 156-59-2 NJDWQI RfD (1994) 0.01 mg/kg-day NJDWQI RfD
trans-1,2-Dichloroethene 156-60-5 NJDWQI RfD (1994) 0.017 mg/kg-day
2,4-Dichlorophenol 120-83-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1988) 0.003 mg/kg-day ABS 0.1 PPRTV SF (2016)
1,2-Dichloropropane 78-87-5 PPRTV Slope Factor (SF) PPRTV RfD 0.037 (mg/kg-day)-1 PPRTV RfD (2016) 0.04 mg/kg-day IRIS SF (2000)
1,3-Dichloropropene (cis and trans) 542-75-6 IRIS Slope Factor (SF) IRIS RfD 0.1 (mg/kg-day)-1 IRIS RfD (2000) 0.03 mg/kg-day
Dieldrin 60-57-1 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS SF (1993) 16 (mg/kg-day)-1 IRIS RfD (1990) 0.00005 mg/kg-day ABS 0.1
Diethylphthalate 84-66-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1993) 0.8 mg/kg-day ABS 0.1
2,4-Dimethylphenol 105-67-9 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1990) 0.02 mg/kg-day ABS 0.1
Di-n-butylphthalate 84-74-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1990) 0.1 mg/kg-day ABS 0.1
2,4-Dinitrophenol 51-28-5 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1991) 0.002 mg/kg-day ABS 0.1
2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture) 25321-146 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1990) 0.68 (mg/kg-day)-1 ABS 0.1
Di-n-octylphthalate 117-84-0 PPRTV RfD with a dermal absorption fraction (ABS) PPRTV RfD (2012) 0.01 mg/kg-day ABS 0.1 IRIS SF (2013)
1,4-Dioxane 123-91-1 IRIS Slope Factor (SF) IRIS RfD 0.1 (mg/kg-day)-1 IRIS RfD (2010) 0.03 mg/kg-day
Endosulfan I and Endosulfan II 115-29-7 IRIS RfD
Endrin 72-20-8 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1991) 0.0003 mg/kg-day ABS 0.1
Ethylbenzene 100-41-4 IRIS RfD7 IRIS RfD (1991) 0.1 mg/kg-day
Extractable Petroleum Hydrocarbons (EPH) (Category 1) various N.J.A.C. 7:26D-Appendix 2, Equation 5 See Table 1a-EPH Toxicity (below)
Extractable Petroleum Hydrocarbons (EPH) (Category 2) various N.J.A.C. 7:26D-Appendix 2, Equation 5 See Table 1a-EPH Toxicity (below)
Fluoranthene 206-44-0 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1993) 0.04 mg/kg-day ABS 0.13
Fluorene 86-73-7 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1990) 0.04 mg/kg-day ABS 0.13
alpha-HCH (alpha-BHC) 319-84-6 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) ATSDR RfD with a dermal absorption fraction (ABS) IRIS SF (1993) 6.3 (mg/kg-day)-1 ATSDR RfD (2013) 0.008 mg/kg-day ABS 0.1
beta-HCH (beta-BHC) 319-85-7 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) and Group C carcinogen factor IRIS SF (1993) 1.8 (mg/kg-day)-1 ABS 0.1 Group C carcinogen factor 10
Heptachlor 76-44-8 IRIS Slope Factor (SF) IRIS RfD
Heptachlor epoxide 1024-57-3 IRIS Slope Factor (SF) IRIS RfD
Hexachlorobenzene 118-74-1 IRIS Slope Factor (SF) IRIS RfD
IRIS Slope Factor (SF) IRIS SF (1991) 0.078 (mg/kg-day)-1
Hexachloro-1,3-butadiene 87-68-3 PPRTV RfD with a Group C carcinogen factor PPRTV RfD (2007) 0.001 mg/kg-day Group C carcinogen factor 10
Hexachlorocyclopentadiene 77-47-4 IRIS RfD
IRIS Slope Factor (SF) IRIS SF (2011) 0.04 (mg/kg-day)-
Hexachloroethane 67-72-1 IRIS RfD
n-Hexane 110-54-3 No ingestion-based toxicity factors are available17 None
2-Hexanone 591-78-6 IRIS RfD IRIS Slope Factor (SF) (benzo(a)pyrene-- IRIS RfD (2009) 0.005 mg/kg-day IRIS SF (2017) 1.0E-01(mg/kg-
Indeno(1,2,3-cd) pyrene 193-39-5 adjusted for indeno (1,2,3-cd)pyrene) with a dermal absorption day)-1 (adjusted for indeno(1,2,3-cd) pyrene)
fraction (ABS). IRIS Slope Factor (SF) ABS 0.13
Isophorone 78-59-1 with a dermal absorption fraction (ABS) IRIS SF (1992) 0.00095 (mg/kg-
IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor day)-1 IRIS RfD (2003) 0.2 mg/kg-day ABS 0.1 Group C carcinogen factor 10
Isopropylbenzene 98-82-8 IRIS RfD USEPA IEUBK model for IRIS RfD (1997) 0.1 mg/kg-day IEUBK (1994)
Lead 7439-92-1 children USEPA ALM for adults Children ALM (1996) Adults
CalEPA Slope Factor (SF) with a 1.1 (mg/kg-day)-1
Lindane (gamma-HCH) (gamma-BHC) 58-89-9 dermal absorption fraction (ABS) IRIS RfD (1988) 0.0003 mg/kg-day
IRIS RfD with a dermal absorption fraction (ABS) ABS 0.04 EPA RSL RfD
Manganese 7439-96-5 EPA RSL RfD (2018) 0.024 mg/kg-day
Mercury 7439-97-6 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (1995) 0.0003 mg/kg-day GIABS 0.07
Methoxychlor 72-43-5 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1991) 0.005 mg/kg-day ABS 0.1
Methyl acetate 79-20-9 HEAST RfD HEAST RfD (1997) 1.0 mg/kg-day
NJDWQI Slope Factor NJDWQI SF (1994) 0.014 (mg/kg-day)-
Methylene chloride 75-09-2 (SF) IRIS RfD 1 IRIS RfD (2011) 0.006 mg/kg-day
2-Methylnaphthalene 91-57-6 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (2003) 0.004 mg/kg-day ABS 0.13
4-Methyl-2-pentanone 108-10-1 No ingestion-based toxicity factors are available None
2-Methylphenol 95-48-7 IRIS RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor IRIS RfD (2008) 0.05 mg/kg-day ABS 0.1 Group C carcinogen factor 10
4-Methylphenol 106-44-5 ATSDR RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor ATSDR RfD (2013) 0.1 mg/kg-day ABS 0.1 Group C carcinogen factor 10
NJDWQI RfD (1994)
NJDWQI RfD with a 0.01 mg/kg-day
Methyl tert-butyl ether (MTBE) 1634-04-4 Group C carcinogen factor8 (RfD includes Group C Carcinogen factor adjustment of 10)
Naphthalene 91-20-3 NJDWQI RfD with a dermal absorption fraction (ABS) and a Group C carcinogen factor NJDWQI RfD (1994) 0.041 mg/kg-day ABS 0.13 (RfD includes Group C Carcinogen factor adjustment of 10)
Nickel 7440-02-0 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (1996) 0.02 mg/kg-day GIABS 0.04 IRIS SF (2009)
4-Nitroaniline 100-01-6 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS) 0.02 (mg/kg-day)-1 PPRTV RfD (2009) 0.004 mg/kg-day 0.0049 (mg/kg-day)-1 ABS 0.1
Nitrobenzene 98-95-3 IRIS RfD IRIS RfD (2009) 0.002 mg/kg-day
N-Nitroso-di-n-propylamine 621-64-7 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1993) 7.0 (mg/kg-day)-1 ABS 0.1
N-Nitrosodiphenylamine 86-30-6 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1993) 0.0049 (mg/kg-day)-1 ABS 0.1
2,2'-Oxybis(1-choloropropane) 108-60-1 IRIS RfD IRIS RfD (1991) 0.04 mg/kg-day
Pentachlorophenol 87-86-5 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS RfD with a dermal absorption fraction (ABS) IRIS SF (2010) 0.4 (mg/kg-day)-1 IRIS RfD (2010) 0.005 mg/kg-day ABS 0.25
Phenol 108-95-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (2002) 0.3 mg/kg-day ABS 0.1
Polychlorinated biphenyls (PCBs) 1336-36-3 NJDWQI Slope Factor (SF) with a dermal absorption fraction (ABS) NJDWQI SF (1994) 2 (mg/kg-day)-1 ABS 0.14
Pyrene 129-00-0 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1993) 0.03 mg/kg-day ABS 0.13
Selenium 7782-49-2 IRIS RfD IRIS RfD (1991) 0.005 mg/kg-day
Silver 7440-22-4 IRIS RfD with a gastrointestinal absorption fraction (GIABS) IRIS RfD (1996) 0.005 mg/kg-day GIABS 0.04
Styrene 100-42-5 IRIS RfD IRIS RfD (1990) 0.2 mg/kg-day
NJDEP RfD (1997) 0.018 mg/kg-day
Tertiary butyl alcohol (TBA) 75-65-0 NJDEP RfD with a Group C carcinogen factor (RfD includes Group C Carcinogen factor adjustment of 10)
1,2,4,5-Tetrachlorobenzene 95-94-3 IRIS RfD
2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (2012) 7E-10 mg/kg-day ABS 0.03 IRIS SF (2010)
1,1,2,2-Tetrachloroethane 79-34-5 IRIS Slope Factor (SF) IRIS RfD9 0.2 (mg/kg-day)-1 IRIS RfD (2010) 0.02 mg/kg-day IRIS SF (2012)
Tetrachloroethene (PCE) 127-18-4 IRIS Slope Factor (SF) IRIS RfD10 0.0021 (mg/kg-day)-1 IRIS RfD (2012) 0.006 mg/kg-day
2,3,4,6-Tetrachlorophenol 58-90-2 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1992) 0.03 mg/kg-day ABS 0.1
Toluene 108-88-3 IRIS RfD IRIS RfD (2005) 0.08 mg/kg-day
Toxaphene 8001-35-2 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) IRIS SF (1991) 1.1 (mg/kg-day)-1 ABS 0.1 IRIS RfD (1996)
1,2,4-Trichlorobenzene 120-82-1 IRIS RfD11 0.01 mg/kg-day
1,1,1-Trichloroethane 71-55-6 IRIS RfD12 IRIS RfD (2007) 2 mg/kg-day IRIS SF (2011)
Trichloroethene (TCE) 79-01-6 IRIS Slope Factor (SF)14 IRIS RfD 0.046 (mg/kg-day)-1 IRIS RfD (2011) 0.0005 mg/kg-day
Trichlorofluoromethane 75-69-4 IRIS RfD IRIS RfD (1992) 0.3 mg/kg-day
2,4,5-Trichlorophenol 95-95-4 IRIS RfD with a dermal absorption fraction (ABS) IRIS RfD (1988) 0.1 mg/kg-day ABS 0.1
2,4,6-Trichlorophenol 88-06-2 IRIS Slope Factor (SF) with a dermal absorption fraction (ABS) PPRTV RfD with a dermal absorption fraction (ABS) IRIS SF (1994) 0.011 (mg/kg-day)-1 PPRTV RfD (2007) 0.001 mg/kg-day ABS 0.1
1,1,2-Trichloro-1,2,2-trifluoroethane 76-13-1 No ingestion-based toxicity factors are available15 None
1,2,4-Trimethylbenzene 95-63-6 IRIS RfD IRIS RfD (2016) 0.01 mg/kg-day
Vanadium 7440-62-2 EPA RSL RfD with a gastrointestinal absorption fraction EPA RSL RfD (2018) 0.005 mg/kg-day GIABS 0.026
Vinyl Chloride 75-01-4 IRIS Slope Factor (SF) IRIS SF (2000) 0.72 (mg/kg-day)-
IRIS RfD16 1 IRIS RfD (2000) 0.003 mg/kg-day NJDWQI RfD
Xylenes 1330-20-7 NJDWQI RfD (1994) 0.15 mg/kg-day
Zinc 7440-66-6 IRIS RfD IRIS RfD (2005) 0.3 mg/kg-day

Table 1a--EPH Toxicity

Applies to both:

EPH - Category 1 (Number 2 Heating Oil/Diesel Fuel)

EPH - Category 2 (Heavier petroleum products)

Note: EPH excludes lighter petroleum products including gasoline and mineral spirits

Effective Carbon Range Aliphatics Surrogate Toxicity Factor Toxicity Factor Reference Source
9 - 12 PHC Mixture RfD 0.10 mg/kg-day ABS 0.1 Canada 2000 and MADEP 2003
12 - 16 PHC Mixture RfD 0.10 mg/kg-day ABS 0.1 Canada 2000 and MADEP 2003
16 - 21 White Mineral Oil RfD 2.0 mg/kg-day ABS 0.1 TPHCWG 1997 and MADEP 2003
21 - 40 White Mineral Oil RfD 2.0 mg/kg-day ABS 0.1 TPHCWG 1997 and MADEP 2003

Effective Carbon Range Aromatics Surrogate Toxicity Factor Toxicity Factor Reference Source
10 - 12 Naphthalene RfD 0.041 mg/kg-day ABS 0.13 NJDWQI (1994)
12 - 16 Acenaphthene RfD 0.06 mg/kg-day ABS 0.13 IRIS (1994)
16 - 21 Fluorene RfD 0.04 mg/kg-day ABS 0.13 IRIS (1990)
21 - 36 Fluoranthene RfD 0.04 mg/kg-day IRIS (1993)

1 Both the NJDWQI slope factor and IRIS RfD for benzene are based on a route to route conversion of an inhalation study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.

2 Although a NJDWQI RfD for 2-butanone exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.

3 Although a CalEPA slope factor for chloroform exists, the USEPA believes there is a threshold effect for cancer. As such, an RfD based soil remediation standard is protective of both cancer and non-cancer health endpoints.

4 Although a CalEPA Slope Factor for 1,4-dichlorobenzene exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for 1,4-dichlorobenzene using this slope factor.

5 Although a NJDWQI RfD for 1,1-dichloroethane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route to route conversion of toxicity factors.

6 Although a PPRTV RfD for 1,2-dichloroethane exists, it is listed as an appendix value. PPRTV appendix values are based on a study(s) that has flaws as determined by the USEPA. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards.

7 Although a CalEPA slope factor for ethylbenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.

8 Although a CalEPA slope factor for methyl tert-butyl ether exists, there are questions about the study used to develop the slope factor. As such, the Department has decided not to develop an ingestion-dermal soil remediation standard for methyl tert-butyl ether using this slope factor.

9Although an NJDWQI RfD for 1,1,2,2-tetrachloroethane exists, the Department has decided to use an IRIS RfD to develop a non-cancer-based ingestion-dermal soil remediation standard as the IRIS RfD is based on a newer toxicology assessment.

10 Although an NJDWQI slope factor for tetrachloroethene exists, the Department has decided that the existing IRIS Slope Factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor). An ingestion-dermal soil remediation standard for tetrachloroethene can also be developed using an IRIS RfD. The RfD uses the newest PBPK models (extrapolating from an inhalation RfC to oral RfD).

11Although an NJDWQI RfD for 1,2,4-trichlorobenzene exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors. In addition, a USEPA PPRTV slope factor for 1,2,4-trichlorobenzene is available, however the Slope Factor is based on a controversial mouse liver tumor study that many researchers have dismissed. The Department has decided not to develop an ingestion-dermal soil remediation standard based on the PPRTV slope factor.

12 Although an NJDWQI RfD for 1,1,1-trichloroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.

13 Although an NJDWQI slope factor for 1,1,2-trichloroethane exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.

14 Although an NJDWQI slope factor for trichloroethene exists, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard. The IRIS slope factor uses the newest PBPK models (extrapolating from an inhalation unit risk factor to an oral slope factor).

15 Although an IRIS RfD for 1,1,2-Trichloro-1,2,2-trifluoroethane exists, it is based on an inhalation route-to-route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.

16 Although an NJDWQI slope factor exists for vinyl chloride, the Department determined that the IRIS slope factor is a scientifically better toxicity value to develop a cancer-based ingestion-dermal soil remediation standard.

*17 Although an NJDWQI RfD (1994) for n-hexane exists, it is based on an inhalation route to route conversion. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route to route conversion of toxicity factors. This policy conforms with USEPA policy concerning route to route conversion of toxicity factors.

Table 2-Soil Inhalation Toxicity Factors

Contaminant CAS No. Soil Inhalation Recommendation Soil Inhalation Toxicity Factor(s)
Acenaphthene 83-32-9 No inhalation-based toxicity factors are available18 None
Acetone 67-64-1 No inhalation-based toxicity factors are available1 None
No inhalation-based
Acetophenone 98-86-2 toxicity factors are available2 None
Aldrin 309-00-2 No inhalation-based toxicity factors are available17 None
Aluminum 7429-90-5 PPRTV RfC PPRTV RfC (2006) 5E-03 mg/m3
Anthracene 120-12-7 No inhalation-based toxicity factors are available18 None
Antimony 7440-36-0 No inhalation-based toxicity factors are available19 None
Arsenic 7440-38-2 IRIS IUR IRIS IUR (1998) 4.3E-03 (ug/m3)-1
No inhalation-based
Atrazine 1912-24-9 toxicity factors are available None
Barium 7440-39-3 HEAST RfC HEAST RfC (1997) 5E-04 mg/m3
Benzaldehyde 100-52-7 No inhalation-based toxicity factors are available None
Benzene 71-43-2 IRIS IUR IRIS RfC IRIS IUR (2000) 7.8E-06 (ug/m3)-1 IRIS RfC (2003) 3E-02 mg/m3
Benzo(a)anthracene 56-55-3 IRIS IUR (benzo(a) pyrene) adjusted for benzo(a)anthracene IRIS IUR (2017) 6.0E-05 (ug/m3)-1 v (adjusted for benzo(a) anthracene)
Benzo(a)pyrene 50-32-8 IRIS IUR IRIS RfC IRIS IUR (2017) 6.0E-04 (ug/m3)-1 IRIS RfC (2017) 2.0E-06 mg/m3
Benzo(b)fluoranthene 205-99-2 IRIS IUR (benzo(a) pyrene) adjusted for benzo(b)fluoranthene IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for benzo (b)fluoranthene)
Benzo(k)fluoranthene 207-08-9 IRIS IUR (benzo(a) pyrene) adjusted for benzo(k) fluoranthene IRIS IUR (2017) 6.0E-06 (ug/m3)-1 (adjusted for benzo (k) fluoranthene) IRIS IUR (1998)
Beryllium 7440-41-7 IRIS IUR IRIS RfC 2.4E-03 (ug/m3)-1 IRIS RfC (1998) 2E-05 mg/m3
1,1'-Biphenyl 92-52-4 No inhalation-based toxicity factors are available None
Bis(2-chloroethoxy) methane 111-91-1 No inhalation-based toxicity factors are available None
Bis(2-chloroethyl) ether 111-44-4 No inhalation-based toxicity factors are available17 None
Bis(2-ethylhexyl) phthalate 117-81-7 No inhalation-based toxicity factors are available17 None
Bromodichloromethane 75-27-4 No inhalation-based toxicity factors are available17 None
No inhalation-based
Bromoform 75-25-2 toxicity factors are available17 None
Bromomethane 74-83-9 IRIS RfC IRIS RfC (1992) 5E-03 mg/m3
2-Butanone 78-93-3 IRIS RfC3 IRIS RfC (2003) 5E+00 mg/m3
Butylbenzylphthalate 85-68-7 No inhalation-based toxicity factors are available None
Cadmium 7440-43-9 IRIS IUR ATSDR RfC IRIS IUR (1992) 1.8E-03 (ug/m3)-1 ATSDR RfC (2013) 1E-05 mg/m3
Caprolactam 105-60-2 CalEPA RfC CalEPA RfC (2013) 2.2E-03 mg/m3
Carbon disulfide 75-15-0 IRIS RfC IRIS RfC (1995) 7E-01 mg/m3
Carbon tetrachloride 56-23-5 IRIS IUR IRIS RfC IRIS IUR (2010) 6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3 7
Chlordane (alpha plus gamma mixture) 57-74-9 IRIS RfC IRIS RfC (1998) 7E-04 mg/m3
4-Chloroaniline 106-47-8 No inhalation-based toxicity factors are available None
Chlorobenzene 108-90-7 PPRTV RfC PPRTV RfC (2006) 5E-02 mg/m3
Chloroethane 75-00-3 IRIS RfC IRIS RfC (1991)
ATSDR RfC No other inhalation- ATSDR RfC (2013)
Chloroform 67-66-3 based toxicity factors are available17 1E+01 mg/m3 9.8E-02 mg/m3
Chloromethane 74-87-3 IRIS RfC4 No inhalation-based IRIS RfC (2001) 9E-02 mg/m3
2-Chloronaphthalene 91-58-7 toxicity factors are available None
2-Chlorophenol 95-57-8 No inhalation-based toxicity factors are available17 None
Chrysene 218-01-9 IRIS IUR (benzo(a) pyrene) adjusted for chrysene IRIS IUR (2017) 6.0E-07 (ug/m3)-1 (adjusted for chrysene)
Cobalt 7440-48-4 PPRTV IUR PPRTV RfC PPRTV IUR (2008) 9E-03(ug/m3)-1 PPRTV RfC (2008) 6E-06 mg/m3
Copper 7440-50-8 No inhalation-based toxicity factors are available5 None
Cyanide 57-12-5 IRIS RfC IRIS RfC (2010) 8E-04 mg/m3
Cyclohexane 110-82-7 IRIS RfC IRIS RfC (2003) 6E+00 mg/m3
4,4'-DDD 72-54-8 No inhalation-based toxicity factors are available17 None
4,4'-DDE 72-55-9 No inhalation-based toxicity factors are available17 None
4,4'-DDT 50-29-3 No inhalation-based toxicity factors are available17 None
Dibenz(a,h)anthracene 53-70-3 IRIS IUR (benzo(a) pyrene) adjusted for dibenzo(a,h) anthracene IRIS IUR (2017) 6.0E-04(ug/m3)-1 (adjusted for dibenzo(a,h) anthracene)
Dibromochloromethane 124-48-1 No inhalation-based toxicity factors are available17 None PPRTV IUR (2006)
1,2-Dibromo-3-chloropropane 96-12-8 PPRTV IUR IRIS RfC 6E-03 (ug/m3)-1 IRIS RfC (1991) 2E-04 mg/m3
1,2-Dibromoethane 106-93-4 IRIS IUR IRIS RfC IRIS IUR (2004) 6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3
1,2-Dichlorobenzene 95-50-1 HEAST RfC HEAST RfC (1997) 2E-01 mg/m3
1,3-Dichlorobenzene 541-73-1 No inhalation-based toxicity factors are available None
1,4-Dichlorobenzene 106-46-7 IRIS RfC No other inhalationbased toxicity factors are available17 IRIS RfC (1994) 8E-01 mg/m3
3,3'-Dichlorobenzidine 91-94-1 No inhalation-based toxicity factors are available None
Dichlorodifluoromethane 75-71-8 No inhalation-based toxicity factors are available6 None
1,1-Dichloroethane 75-34-3 No inhalation-based toxicity factors are available7 None
1,2-Dichloroethane 107-06-2 PPRTV RfC No other inhalationbased toxicity factors are available17 PPRTV RfC (2010) 7E-03 mg/m3
1,1-Dichloroethene 75-35-4 A soil inhalation remediation standard can be developed using an IRIS RfC with a Group C carcinogen factor IRIS RfC (2002/2005) 2E-01 mg/m3 RfC Group C carcinogen factor 10
cis-1,2-Dichloroethene 156-59-2 No inhalation-based toxicity factors are available None
trans-1,2-Dichloroethene 156-60-5 No inhalation-based toxicity factors are available8 None
2,4-Dichlorophenol 120-83-2 No inhalation-based toxicity factors are available17 None
1,2-Dichloropropane 78-87-5 PPRTV IUR IRIS RfC PPRTV IUR (2016) 3.7E-06 (ug/m3)-1 IRIS RfC (1991) 4E-03 mg/m3
1,3-Dichloropropene (cis and trans) 542-75-6 IRIS IUR IRIS RfC IRIS IUR (2000) 4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3
Dieldrin 60-57-1 No inhalation-based toxicity factors are available None
Diethylphthalate 84-66-2 No inhalation-based toxicity factors are available17 None
2,4-Dimethylphenol 105-67-9 No inhalation-based toxicity factors are available17 None
Di-n-butylphthalate 84-74-2 No inhalation-based toxicity factors are available17 None
2,4-Dinitrophenol 51-28-5 No inhalation-based toxicity factors are available17 None
2,4-Dinitrotoluene /2,6-Dinitrotoluene (mixture) 25321-14 6 No inhalation-based toxicity factors are available17 None
Di-n-octylphthalate 117-84-0 No inhalation-based toxicity factors are available9 None
1,4-Dioxane 123-91-1 IRIS IUR IRIS RfC IRIS IUR (2013) 5.0E-06 (ug/m3)-1 IRIS RfC (2013) 3E-02 mg/m3
Endosulfan I and Endosulfan II (alpha and beta) 115-29-7 No inhalation-based toxicity factors are available17 None
Endrin 72-20-8 No inhalation-based toxicity factors are available17 None CalEPA IUR (2007)
Ethylbenzene 100-41-4 CalEPA IUR IRIS RfC 2.5E-06 (ug/m3)-1 IRIS RfC (1991) 1E+00 mg/m3
Extractable Petroleum Hydrocarbons (EPH) (Category 1) various No inhalation-based toxicity factors are available None
Extractable Petroleum Hydrocarbons (EPH) (category 2) various No inhalation-based toxicity factors are available None
Fluoranthene 206-44-0 No inhalation-based toxicity factors are available18 None
Fluorene 86-73-7 No inhalation-based toxicity factors are available18 None
alpha-HCH (alpha-BHC) 319-84-6 No inhalation-based toxicity factors are available17 None
beta-HCH (beta-BHC) 319-85-7 No inhalation-based toxicity factors are available17 None
Heptachlor 76-44-8 No inhalation-based toxicity factors are available17 None
Heptachlor epoxide 1024-57-3 No inhalation-based toxicity factors are available17 None
Hexachlorobenzene 118-74-1 No inhalation-based toxicity factors are available17 None
Hexachloro-1,3-butadiene 87-68-3 No inhalation-based toxicity factors are available17 None
Hexachlorocyclopentadiene 77-47-4 IRIS RfC IRIS RfC (2001) 2E-04 mg/m3
Hexachloroethane 67-72-1 IRIS RfC IRIS RfC (2011) 3E-02 mg/m3
n-Hexane 110-54-3 IRIS RfC IRIS RfC (2005) 7E-01 mg/m3
2-Hexanone 591-78-6 IRIS RfC IRIS RfC (2009) 3E-02 mg/m3
Indeno(1,2,3,-cd) pyrene 193-39-5 IRIS IUR (benzo(a) pyrene) adjusted for indeno(1,2,3,-cd) pyrene. IRIS IUR (2017) 6.0E-05 (ug/m3)-1 (adjusted for indeno(1,2,3,-cd) pyrene)
Isophorone 78-59-1 CalEPA RfC CalEPA RfC (2001) 2E-00 mg/m3
Isopropylbenzene 98-82-8 IRIS RfC IRIS RfC (1997) 4E-01 mg/m3
Lead 7439-92-1 No inhalation-based toxicity factors are available17 None
Lindane (gamma-HCH) (gamma-BHC) 58-89-9 No inhalation-based toxicity factors are available17 None
Manganese 7439-96-5 IRIS RfC IRIS RfC (1993) 5E-05 mg/m3
Mercury 7439-97-6 IRIS RfC IRIS RfC (1995) 3E-04 mg/m3
Methoxychlor 72-43-5 No inhalation-based toxicity factors are available17 None
Methyl acetate 79-20-9 No inhalation-based toxicity factors are available None
IRIS IUR (2011)
Methylene chloride 75-09-2 IRIS IUR IRIS RfC 1E-08 (ug/m3)-1 IRIS RfC (2011) 6E-01 mg/m3
2-Methylnaphthalene 91-57-6 No inhalation-based toxicity factors are available18 None
4-Methyl-2-pentanone 108-10-1 IRIS RfC IRIS RfC (2003) 3E+00 mg/m3
2-Methylphenol 95-48-7 No inhalation-based toxicity factors are available17 None
4-Methylphenol 106-44-5 No inhalation-based toxicity factors are available17 None
Methyl tert-butyl ether (MTBE) 1634-04-4 CalEPA IUR IRIS RfC with a Group C carcinogen factor CalEPA IUR (1999) 2.6E-07 (ug/m3)-1 IRIS RfC (1993) 3E+00 mg/m3 Group C carcinogen factor 10
Naphthalene 91-20-3 CalEPA IUR IRIS RfC with a Group C carcinogen factor CalEPA IUR (2011) 3.4E-05 (ug/m3)-1 IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen factor 10
Nickel 7440-02-0 IRIS IUR CalEPA RfC IRIS IUR (1987/2006) 2.4E-04 (ug/m3)-1 CalEPA RfC (2012) 1.4E-05 mg/m3
4-Nitroaniline 100-01-6 PPRTV RfC PPRTV RfC (2009) 6E-03 mg/m3
IRIS IUR (2009)
Nitrobenzene 98-95-3 IRIS IUR IRIS RfC 4E-05 (ug/m3)-1 IRIS RfC (2009)
9E-03 mg/m3
No inhalation-based
N-Nitroso-di-n- propylamine 621-64-7 toxicity factors are available17 None
No inhalation-based
N-Nitrosodiphenylamine 86-30-6 toxicity factors are available17 None
No inhalation-based
2,2'-Oxybis(1-choloropropane) 108-60-1 toxicity factors are available None
No inhalation-based
Pentachlorophenol 87-86-5 toxicity factors are None
available17
Phenol 108-95-2 CalEPA RfC CalEPA RfC (2000) 2E-01 mg/m3
No inhalation-based
Polychlorinated biphenyls (PCBs) 1336-36-3 toxicity factors are None
available17 No inhalation-based
Pyrene 129-00-0 toxicity factors are None
available18 No inhalation-based
Selenium 7782-49-2 toxicity factors are None
available No inhalation-based
Silver 7440-22-4 toxicity factors are None
available17
Styrene 100-42-5 IRIS RfC10 IRIS RfC (1992) 1E+00 mg/m3
No inhalation-based
Tertiary butyl alcohol (TBA) 75-65-0 toxicity factors are None
available17 No inhalation-based
1,2,4,5-Tetrachlorobenzene 95-94-3 toxicity factors are None
available No inhalation-based
2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 toxicity factors are None
available No inhalation-based
1,1,2,2-Tetrachloroethane 79-34-5 toxicity factors are None
available17
Tetrachloroethene (PCE) 127-18-4 IRIS IUR IRIS RfC IRIS IUR (2012) 2.6E-07 (ug/m3)-1 IRIS RfC (2012) 4E-02 mg/m3
No inhalation-based
2,3,4,6-Tetrachlorophenol 58-90-2 toxicity factors are None
available IRIS RfC (2005)
Toluene 108-88-3 IRIS RfC 5E+00 mg/m3
No inhalation-based
Toxaphene 8001-35-2 toxicity factors are None
available17
1,2,4-Trichlorobenzene 120-82-1 PPRTV RfC PPRTV RfC (2009) 2E-03 mg/m3
IRIS RfC (2007)
1,1,1-Trichloroethane 71-55-6 IRIS RfC11 5E+00 mg/m3
1,1,2-Trichloroethane 79-00-5 No inhalation-based toxicity factors are available12 None
IRIS IUR (2011) 4.1E-
Trichloroethene (TCE) 79-01-6 IRIS IUR IRIS RfC13 06 (ug/m3)-1 IRIS RfC (2011) 2E-03 mg/m3
Trichlorofluoromethane 75-69-4 No inhalation-based toxicity factors are available14 None
2,4,5-Trichlorophenol 95-95-4 No inhalation-based toxicity factors are available17 None
2,4,6-Trichlorophenol 88-06-2 No inhalation-based toxicity factors are available17 None
1,1,2-Trichloro-1,2,2-trifluoroethane 76-13-1 PPRTV RfC PPRTV RfC (2016) 5E+00 mg/m3
1,2,4-Trimethylbenzene 95-63-6 IRIS RfC IRIS RfC (2016) 6E-02 mg/m3
Vanadium 7440-62-2 ATSDR RfC 1E-04 mg/m3
IRIS IUR (2000) 4.4E-
Vinyl Chloride 75-01-4 IRIS IUR IRIS RfC15 06 (ug/m3)-1 IRIS RfC (2000) 1E-01 mg/m3
Xylenes 1330-20-7 IRIS RfC IRIS RfC (2003) 1.E-01 mg/m3
Zinc 7440-66-6 No inhalation-based toxicity factors are available16 None

1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.

2 A HEAST RfC exists for acetophenone, but a subsequent PPRTV review (2010) questions the use of the HEAST RfC.

3 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with USEPA policy concerning route-to-route conversion of toxicity factors.

4 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."

5 A CalEPA RfC that once existed for copper has been retracted by CalEPA.

6 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. As the HEAST RfC developed using the Prendergast study, the Department decided not to use this RfC in the development of a soil remediation standard.

7 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.

8A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC."

9 A 1985 USEPA IUR that once existed for di-n-octylphthalate has been retracted by the USEPA.

10 A HEAST 1991 IUR exists for styrene but USEPA NCEA does not recommend its use.

11 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.

12 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop soil remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.

13 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.

14 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.

15 The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.

16 A CalEPA RfC that once existed for zinc has been retracted by CalEPA.

*17There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-

route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of soil remediation standards based on route-to-route conversion of toxicity factors.

18The 2008 inhalation toxicity factor was based on an equivalency factor from Nisbet and LaGoy (1992). Nisbet and LaGoy did not conduct any original research and relied on studies using dermal application and subcutaneous injection, with one study using intrapulmonary administration (not inhalation). The Nisbet and LaGoy study develops TEFs for PAHs compared to BP. The Department did not use this study because it was not derived from an inhalation study.

19The former IRIS RfC was withdrawn.

Table 3--Indoor Air Toxicity Factors

Contaminant CAS No. VI Recommendation VI Toxicity Factor (s)
Acenaphthene 83-32-9 Not applicable No inhalation-based Not applicable
Acetone 67-64-1 toxicity factors are available1 None
Acetophenone 98-86-2 Not applicable Not applicable
Aldrin 309-00-2 Not applicable Not applicable
Aluminum 7429-90-5 Not applicable Not applicable
Anthracene 120-12-7 Not applicable Not applicable
Antimony 7440-36-0 Not applicable Not applicable
Arsenic 7440-38-2 Not applicable Not applicable
Atrazine 1912-24-9 Not applicable Not applicable
Barium 7440-39-3 Not applicable Not applicable
Benzaldehyde 100-52-7 Not applicable Not applicable
Benzene 71-43-2 IRIS IUR IRIS IUR (2000)
IRIS RfC 7.8E-06 (ug/m3)-1
IRIS RfC (2003) 3E-02 mg/m3
Benzo(a)anthracene 56-55-3 Not applicable Not applicable
Benzo(a)pyrene 50-32-8 Not applicable Not applicable
Benzo(b)fluoranthene 205-99-2 Not applicable Not applicable
Benzo(k)fluoranthene 207-08-9 Not applicable Not applicable
Beryllium 7440-41-7 Not applicable Not applicable
1,1'-Biphenyl 92-52-4 Not applicable Not applicable
Bis(2-chloroethoxy) methane 111-91-1 Not applicable Not applicable
Bis(2-chloroethyl) ether 111-44-4 Not applicable Not applicable
Bis(2-ethylhexyl) phthalate 117-81-7 Not applicable Not applicable
Bromodichloromethane 75-27-4 No inhalation-based toxicity factors are available13 None
No inhalation-based
Bromoform 75-25-2 toxicity factors are available13 None
Bromomethane 74-83-9 IRIS RfC IRIS RfC (1992) 5E-03 mg/m3
2-Butanone 78-93-3 VI standard can be developed using IRIS RfC2 IRIS RfC (2003)
5E+00 mg/m3
Butylbenzylphthalate 85-68-7 Not applicable Not applicable
Cadmium 7440-43-9 Not applicable Not applicable
Caprolactam 105-60-2 Not applicable Not applicable
Carbon disulfide 75-15-0 IRIS RfC IRIS RfC (1995) 7E-01 mg/m3
Carbon tetrachloride 56-23-5 IRIS IUR IRIS IUR (2010)
IRIS RfC 6E-06 (ug/m3)-1 IRIS RfC (2010) 1E-01 mg/m3
Chlordane 57-74-9 Not applicable Not applicable
(alpha plus gamma mixture) 4-Chloroaniline 106-47-8 Not applicable Not applicable
Chlorobenzene 108-90-7 PPRTV RfC PPRTV RfC (2006)5E-02 mg/m3
Chloroethane 75-00-3 IRIS RfC IRIS RfC (1991) 1E+01 mg/m3
Chloroform 67-66-3 ATSDR RfC ATSDR RfC (2013)
No other inhalationbased toxicity factors are available13 9.8E-02 mg/m3
Chloromethane 74-87-3 IRIS RfC3 IRIS RfC (2001) 9E-02 mg/m3
2-Chloronaphthalene 91-58-7 Not applicable Not applicable
2-Chlorophenol 95-57-8 Not applicable Not applicable
Chrysene 218-01-9 Not applicable Not applicable
Cobalt 7440-48-4 Not applicable Not applicable
Copper 7440-50-8 Not applicable Not applicable
Cyanide 57-12-5 Not applicable Not applicable
Cyclohexane 110-82-7 IRIS RfC IRIS RfC (2003) 6E+00 mg/m3
4,4'-DDD 72-54-8 Not applicable Not applicable
4,4'-DDE 72-55-9 Not applicable Not applicable
4,4'-DDT 50-29-3 Not applicable Not applicable
Dibenz(a,h)anthracene 53-70-3 Not applicableNo inhalation-based Not applicable
Dibromochloromethane 124-48-1 toxicity factors are available13 None
1,2-Dibromo-3-chloropropane 96-12-8 Not applicable Not applicable
1,2-Dibromoethane 106-93-4 IRIS IUR IRIS IUR (2004)
IRIS RfC 6E-04 (ug/m3)-1 IRIS RfC (2004) 9E-03 mg/m3
1,2-Dichlorobenzene 95-50-1 HEAST RfC HEAST RfC (1997)2E-01 mg/m3
No inhalation-based
1,3-Dichlorobenzene 541-73-1 toxicity factors are available None
1,4-Dichlorobenzene 106-46-7 IRIS RfC IRIS RfC (1996)
No other inhalationbased toxicity factors are available13 8E-01 mg/m3
3,3'-Dichlorobenzidine 91-94-1 Not applicableNo inhalation-based Not applicable
Dichlorodifluoromethane 75-71-8 toxicity factors are available4 None
No inhalation-based
1,1-Dichloroethane 75-34-3 toxicity factors are available5 None
1,2-Dichloroethane 107-06-2 PPRTV RfC PPRTV RfC (2010)
No other inhalationbased toxicity factors are available13 7E-03 mg/m3
1,1-Dichloroethene 75-35-4 IRIS RfC with a Group C carcinogen factor IRIS RfC (2002/2005)
2E-01 mg/m3
Group C carcinogen factor 10
No inhalation-based
cis-1,2-Dichloroethene 156-59-2 toxicity factors are available None
No inhalation-based
trans-1,2-Dichloroethene 156-60-5 toxicity factors are available6 None
2,4-Dichlorophenol 120-83-2 78-87-5 PPRTV IUR PPRTV IUR (2016)
IRIS RfC 3.7E-06 (ug/m3)-1
IRIS RfC (1991) 4E-03 mg/m3
1,3-Dichloropropene 5422-75-6 IRIS IUR IRIS IUR (2000)
(cis and trans) IRIS RfC 4E-06 (ug/m3)-1 IRIS RfC (2000) 2E-02 mg/m3
Dieldrin 60-57-1 Not applicable Not applicable
Diethylphthalate 84-66-2 Not applicable Not applicable
2,4-Dimethylphenol 105-67-9 Not applicable Not applicable
Di-n-butylphthalate 84-74-2 Not applicable Not applicable
2,4-Dinitrophenol 51-28-5 Not applicable Not applicable
2,4-Dinitrotoluene /2,6-Dinitrotoluene(mixture) 25321-146 Not applicable Not applicable
Di-n-octyl phthalate 117-84-0 Not applicable Not applicable
1,4-Dioxane 123-91-1 IRIS IUR IRIS IUR (2013)
IRIS RfC 5.0E-06 (ug/m3)-1
IRIS RfC (2013) 3E-02 mg/m3
Endosulfan I and Endosulfan II (alpha and beta) 115-29-7 Not applicable Not applicable
Endrin 72-20-8 Not applicable Not applicable
Ethylbenzene 100-41-4 CalEPA IUR CalEPA IUR (2007)
IRIS RfC 2.5E-06 (ug/m3)-1
IRIS RfC (1991) 1E+00 mg/m3
Extractable Petroleum Hydrocarbons (EPH) (Category 1) various Not applicable Not applicable
Extractable Petroleum Hydrocarbons (EPH) (Category 2) various Not applicable Not applicable
Fluoranthene 206-44-0 Not applicable Not applicable
Fluorene 86-73-7 Not applicable Not applicable
alpha-HCH (alpha-BHC) 319-84-6 Not applicable Not applicable
beta-HCH (beta-BHC) 319-85-7 Not applicable Not applicable
Heptachlor 76-44-8 Not applicable Not applicable
Heptachlor epoxide 1024-57-3 Not applicable Not applicable
Hexachlorobenzene 118-74-1 Not applicable Not applicable
Hexachloro-1,3-butadiene 87-68-3 No inhalation-based toxicity factors are available13 None
Hexachlorocyclopentadiene 77-47-4 Not applicable Not applicable
Hexachloroethane 67-72-1 Not applicable Not applicable
n-Hexane 110-54-3 IRIS RfC IRIS RfC (2005)
7E-01 mg/m3
2-Hexanone 591-78-6 Not applicable Not applicable
Indeno(1,2,3,-cd) pyrene 193-39-5 Not applicable Not applicable
Isophorone 78-59-1 Not applicable Not applicable
Isopropylbenzene 98-82-8 Not applicable Not applicable
Lead 7439-92-1 Not applicable Not applicable
Lindane (gamma-HCH) (gamma-BHC) 58-89-9 Not applicable Not applicable
Manganese 7439-96-5 Not applicable Not applicable
Mercury 7439-97-6 IRIS RfC IRIS RfC (1995) 3E-04 mg/m3
Methoxychlor 72-43-5 Not applicableNo inhalation-based Not applicable
Methyl acetate 79-20-9 toxicity factors are available None
Methylene chloride 75-09-2 IRIS IUR IRIS IUR (2011)
IRIS RfC 1E-08 (ug/m3)-1
IRIS RfC (2011)6E-01 mg/m3
2-Methylnaphthalene 91-57-6 Not applicable Not applicable
4-Methyl-2-pentanone 108-10-1 IRIS RfC IRIS RfC (2003)
3E +00 mg/m3
2-Methylphenol 95-48-7 Not applicable Not applicable
4-Methylphenol 106-44-5 Not applicable Not applicable
Methyl tert-butyl ether (MTBE) 1634-04-4 CalEPA IUR CalEPA IUR (1999)
IRIS RfC 2.6E-07 (ug/m3)-1
IRIS RfC (1993)
3E +00 mg/m3
Naphthalene 91-20-3 CalEPA IUR CalEPA IUR (2004)
IRIS RfC with a Group C 3.4E-05 (ug/m3)-
carcinogen factor 1IRIS RfC (1998) 3E-03 mg/m3 Group C carcinogen
Nickel 7440-02-0 Not applicable Not applicable
4-Nitroaniline 100-01-6 Not applicable Not applicable
Nitrobenzene 98-95-3 Not applicable Not applicable
N-Nitroso-di-n propylamine 621-64-7 Not applicable Not applicable
N-Nitrosodiphenylamine 86-30-6 Not applicable Not applicable
2,2'-Oxybis(1-choloropropane) 108-60-1 Not applicable Not applicable
Pentachlorophenol 87-86-5 Not applicable Not applicable
Phenol 108-95-2 Not applicable Not applicable
Polychlorinated biphenyls (PCBs) 1336-36-3 Not applicable Not applicable
Pyrene 129-00-0 Not applicable Not applicable
Selenium 7782-49-2 Not applicable Not applicable
Silver 7440-22-4 Not applicable Not applicable
Styrene 100-42-5 VI standard can be developed using IRIS RfC7 IRIS RfC (1993)
1E +00 mg/m3
No inhalation-based
Tertiary butyl alcohol (TBA) 75-65-0 toxicity factors are available13 None
1,2,4,5-Tetrachlorobenzene 95-94-3 Not applicable Not applicable
2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 Not applicableNo inhalation-based Not applicable
1,1,2,2-Tetrachloroethane 79-34-5 toxicity factors are available13 None
Tetrachloroethene (PCE) 127-18-4 IRIS IUR IRIS IUR (2012)
IRIS RfC 2.6E-07 (ug/m3)-1
IRIS RfC (2012) 4E-02 mg/m3
2,3,4,6-Tetrachlorophenol 58-90-2 Not applicable Not applicable
Toluene 108-88-3 IRIS RfC IRIS RfC (2005)
5E +00 mg/m3
Toxaphene 8001-35-2 Not applicable Not applicable
1,2,4-Trichlorobenzene 120-82-1 PPRTV RfC PPRTV RfC (2009)2E-03 mg/m3
1,1,1-Trichloroethane 71-55-6 IRIS RfC8 IRIS RfC (2007)
5E +00 mg/m3
No inhalation-based
1,1,2-Trichloroethane 79-00-5 toxicity factors are available9 None
Trichloroethene (TCE) 79-01-6 IRIS IUR IRIS IUR (2011)
IRIS RfC130> 4.1E-06 (ug/m3)-1
IRIS RfC (2011)
2E-03 mg/m3
No inhalation-based
Trichlorofluoromethane 75-69-4 toxicity factors are available131> None
2,4,5-Trichlorophenol 95-95-4 Not applicable Not applicable
2,4,6-Trichlorophenol 88-06-2 Not applicable Not applicable
1,1,2-Trichloro-1,2,2-trifluoroethane 76-13-1 PPRTV RfC PPRTV RfC (2016)5E+00 mg/m3
1,2,4-Trimethylbenzene 95-63-6 IRIS RfC IRIS RfC (2016) 6E-02 mg/m3
Vanadium 7440-62-2 Not applicable Not applicable
Vinyl Chloride 75-01-4 IRIS IUR. IRIS IUR (2000)
IRIS RfC132> 4.4E-06 (ug/m3)-1
IRIS RfC (2000)
1E-01 mg/m3
Xylenes 1330-20-7 IRIS RfC IRIS RfC (2003)1.E-01 mg/m3
Zinc 7440-66-6 Not applicable Not applicable

1 An ATSDR RfC exists for acetone using the results of the Stewart 1975 study. The USEPA IRIS notes that this study should only be used in the development of a short-term exposure RfC and not a long-term (chronic) exposure RfC.

2 A NJDWQI RfC exists for 2-butanone, but the IRIS RfC has been determined by the Department to be more appropriate. The existing NJDWQI RfC is based on a route-to-route conversion of a NJDWQI RfD. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors. This policy conforms with the USEPA policy concerning route-to-route conversion of toxicity factors.

3 A HEAST IUR exists for chloromethane, but a subsequent PPRTV review (2012) states that the use of the HEAST IUR is "Inadequate for an assessment of carcinogenic potential."

4 A HEAST RfC and a PPRTV RfC exist for dichlorodifluoromethane. Both RfCs are derived using the same study (Prendergast 1967). The PPRTV is listed as an appendix value. The PPRTV RfC is listed as an appendix value because the Prendergast study was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. As the HEAST RfC was developed using the Prendergast study data, the Department decided not to use this RfC in the development of a remediation standard.

5 A HEAST RfC exists for 1,1-dichloroethane, but a subsequent PPRTV review (2006) indicated that data were inadequate to derive a chronic exposure RfC for 1,1-dichloroethane. A CalEPA IUR also exists for 1,1-dichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.

6A PPRTV RfC exists for trans-1,2-dichloroethene but a subsequent IRIS assessment (2010) stated "the available inhalation data from the Freund study are insufficient to support reference value derivation and RfC." 7 A HEAST 1991 IUR exists for styrene but the USEPA NCEA does not recommend its use.

8 Although an NJDWQI RfC exists for 1,1,1-trichloroethane, the Department determined that the IRIS RfC is a scientifically better toxicity value to develop a non-cancer-based soil inhalation remediation standard.

9 Although a PPRTV RfC for 1,1,2-trichloroethane exists, it is listed as an appendix value. The PPRTV appendix value is based on a study that was determined by the USEPA to have flaws. It is the Department's Site Remediation and Waste Management Program policy not to use PPRTV appendix values to develop remediation standards. An IRIS IUR also exists for 1,1,2-trichloroethane but is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.

10 The IRIS RfC for trichloroethene is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.

11 A HEAST RfC exists for trichlorofluoromethane, but a subsequent PPRTV review (2009) indicated that data used to derive the RfC were inadequate.

12The IRIS RfC for vinyl chloride is based on a route-to-route conversion of an ingestion study, which was determined to be acceptable by the USEPA as substantiated by additional evaluation including physiologically-based pharmacokinetic modeling.

*13There is an inhalation toxicity factor available for this contaminant, but it is based on a route-to-route conversion of an oral study. The Department's Site Remediation and Waste Management Program policy does not allow, except where warranted with physiologically-based pharmacokinetic modeling, for the development of indoor air remediation standards based on route-to-route conversion of toxicity factors.

References

ALM (Adult Lead Model).2003. Recommendation of the Technical Review Workgroup for Lead for an Approach to Assessing Risks Associated with Adult Lead Exposure to Lead in Soil. USEPA, Office of Solid Waste and Emergency Response, Washington, D.C. EPA-540-R-03-001.

ATSDR (Agency for Toxic Substances and Disease Registry).2018. Minimal Risk Levels for Hazardous Substances. http://www.atsdr.cdc.gov/mrls/mrllist.asp

CalEPA (California Environmental Protection Agency). Office of Environmental Health Hazard Assessment (OEHHA). OEHHA Toxicity Criteria Database. http://www.oehha.ca.gov/risk/chemicalDB/index.asp

Canada 2000: Canadian Council of Ministers of the Environment (CCME). 2000. Canada-Wide Standards for Petroleum Hydrocarbons (PHCs) in soil: Scientific Rationale. Supporting Document.

EPA RSL (United States Environmental Protection Agency). 2018. Regional Screening Levels for

Chemical Contaminants at Superfund Sites. November 2018. http://www.epa.gov/risk/regional-screening-levels-rsls

HEAST--Health Effects Assessment Summary: Annual Update FY 1997. United States Environmental Protection Agency, Office of Research and Development, Office of Emergency and Remedial Response, Washington, DC. NTIS PB97-921199. http://epa-heast.ornl.gov/index.html

IEUBK. 1994. Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children.

USEPA, Office of Solid Waste and Emergency Response, Washington, DC. OSWER9285.7-15-1.

IRIS (Integrated Risk Information System). United States Environmental Protection Agency. http://www.epa . gov/IRIS/

MADEP (Massachusetts Department of Environmental Protection). 2003. Updated Petroleum Standards. Hydrocarbon Toxicity Values for the VPH/EPH/APH Methodology, Final. Office of Research and Standards.

NJDEP (New Jersey Department of Environmental Protection). 1997. Interim Specific Criterion for Tertiary

Butyl Alcohol. Memorandum dated September 12, 1997.

NJDWQI (New Jersey Drinking Water Quality Institute). 1994. Maximum Contaminant Level Recommendation for Hazardous Contaminants in Drinking Water, Appendix A, Health-Based Maximum Contaminant Level Support Documents and Addenda. (A-280 Values).

PPRTV (Provisional Peer Reviewed Toxicity Values for Superfund). United States Environmental Protection Agency. http://hhpprtv.ornl.gov/index.html

TPHCWG (Total Petroleum Hydrocarbon Working Group). 1997. Edwards, D.A., Andriot, M.D., Amoruso, M. A., Tummey, A.C., Bevan, C.J., and Tveit, A. TPHCWG Series: Development of Fraction Specific Reference Doses (RfDs) and Reference Concentrations (RfCs). Volume 4.

TPHCWG (Total Petroleum Hydrocarbon Working Group). 1997. Hayes, L.A., Youngren, S.H., and Nakles, D. V. TPHCWG Series: Development of Fraction Specific Reference Doses (RfDs) and Reference Concentrations (RfCs). Volume 4.

USEPA (United States Environmental Protection Agency). 2004. Risk Assessment Guidance for Superfund Volume I: Human Health Evaluation Manual (Part E, Supplemental Guidance for Dermal Risk Assessment) Final. OSWER 9285.7-02EP. July 2004.

Notes

N.J. Admin. Code 26D app 11
Adopted by 53 N.J.R. 775(b), effective 5/17/2021

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