This case concerns the proper venue for litigating the Clean Air Act’s Renewable Fuel Standards. The EPA argues that its actions pursuant to these standards must go to the D.C. Appeals circuit. This is because the EPA contends that its actions were either nationally applicable, since they affect refineries in multiple circuits, or based on a determination of nationwide scope, since they stem from agency determinations about the Renewable Fuel Standard’s scope. Calumet Shreveport Refinery counters that the actions should not exclusively be litigated in the D.C. Circuit but rather in the applicable appeals circuits across the country, since the EPA’s determinations are not nationally applicable, but rather individualized adjudications on the petitions of hundreds of small, local refineries based on particular local circumstances. This case has important implications for the direction of the Supreme Court’s statutory interpretation, as well as shaping the direction of administrative law and the power allotted to executive agencies.